Literature DB >> 2676706

Cloning of a DNA sequence encoding a major fragment of the 47 kilodalton stress protein homologue of Candida albicans.

R Matthews1, J Burnie.   

Abstract

Part of the gene coding for the immunodominant 47 kDa antigen of the human fungal pathogen Candida albicans was cloned and sequenced. The predicted amino acid sequence was homologous to stress proteins, the most extensive similarity being with the heat shock protein hsp 90 of Saccharomyces cerevisiae. The 47 kDa antigen has diagnostic and therapeutic potential and is the first candidal antigen to be cloned and sequenced.

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Year:  1989        PMID: 2676706     DOI: 10.1016/0378-1097(89)90071-2

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN: 0378-1097            Impact factor:   2.742


  25 in total

Review 1.  Heat shock proteins in immune reactions.

Authors:  E Weigl; P Kopecek; M Raska; S Hradilová
Journal:  Folia Microbiol (Praha)       Date:  1999       Impact factor: 2.099

Review 2.  Cell wall and secreted proteins of Candida albicans: identification, function, and expression.

Authors:  W L Chaffin; J L López-Ribot; M Casanova; D Gozalbo; J P Martínez
Journal:  Microbiol Mol Biol Rev       Date:  1998-03       Impact factor: 11.056

3.  Members of the Hsp70 family of proteins in the cell wall of Saccharomyces cerevisiae.

Authors:  J L López-Ribot; W L Chaffin
Journal:  J Bacteriol       Date:  1996-08       Impact factor: 3.490

4.  Differential Gene Expression of Heat Shock Protein 90 (Hsp90) of Candida albicans obtained from Malaysian and Iranian Patients.

Authors:  Vajihe Khalili; Hojjatollah Shokri; Abdah Md Akim; Ali Reza Khosravi
Journal:  Malays J Med Sci       Date:  2016-05

5.  Isolation and identification of a 92-kDa stress induced protein from Candida albicans.

Authors:  E T Burt; C O'Connor; B Larsen
Journal:  Mycopathologia       Date:  1999       Impact factor: 2.574

6.  A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis.

Authors:  C Bromuro; R La Valle; S Sandini; F Urbani; C M Ausiello; L Morelli; C Fé d'Ostiani; L Romani; A Cassone
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

7.  Structure and regulation of the HSP90 gene from the pathogenic fungus Candida albicans.

Authors:  R K Swoboda; G Bertram; S Budge; G W Gooday; N A Gow; A J Brown
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

8.  Molecular cloning and expression of a 70-kilodalton heat shock protein of Candida albicans.

Authors:  R La Valle; C Bromuro; L Ranucci; H M Muller; A Crisanti; A Cassone
Journal:  Infect Immun       Date:  1995-10       Impact factor: 3.441

9.  Heat shock protein 88 and Aspergillus infection.

Authors:  J P Burnie; R C Matthews
Journal:  J Clin Microbiol       Date:  1991-10       Impact factor: 5.948

10.  Molecular cloning of cDNA and analysis of protein secondary structure of Candida albicans enolase, an abundant, immunodominant glycolytic enzyme.

Authors:  P Sundstrom; G R Aliaga
Journal:  J Bacteriol       Date:  1992-11       Impact factor: 3.490

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