| Literature DB >> 26766585 |
Haritha Mathsyaraja1, Robert N Eisenman2.
Abstract
Myc and its paralog MycN are thought to be functionally redundant, but Myc- and MycN-driven medulloblastomas exhibit distinct phenotypes. In this issue of Cancer Cell, Vo and colleagues (2016) show that this phenotypic difference stems from the preferential ability of Myc, relative to MycN, to bind Miz1 and repress transcription.Entities:
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Year: 2016 PMID： 26766585 DOI： 10.1016/j.ccell.2015.12.009
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743