| Literature DB >> 26766438 |
Jing Yong1, Pamela Itkin-Ansari2, Randal J Kaufman3.
Abstract
Pancreatic β cells synthesize and secrete insulin to increase anabolic metabolism in an organism, and insulin synthesis has long been suspected to inhibit β cell replication. Recently in Cell Metabolism, Szabat et al. (2015) present evidence that deletion of Insulin genes alleviates ER stress and promotes mature β cell replication.Entities:
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Year: 2016 PMID： 26766438 DOI： 10.1016/j.devcel.2015.12.030
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270