Simon Endes1, Emmanuel Schaffner2, Seraina Caviezel2, Julia Dratva2, Christine S Autenrieth2, Miriam Wanner3, Brian Martin3, Daiana Stolz4, Marco Pons5, Alexander Turk6, Robert Bettschart7, Christian Schindler2, Nino Künzli2, Nicole Probst-Hensch2, Arno Schmidt-Trucksäss1. 1. Department of Sport, Exercise and Health, Division of Sports and Exercise Medicine, University of Basel, 4052 Basel, Switzerland. 2. Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland. 3. Divison of Chronic Disease Epidemiology, Department of Epidemiology, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland. 4. Clinic of Pneumology and Respiratory Cell Research, University Hospital, Basel, Switzerland. 5. Division of Pulmonary Medicine, Regional Hospital Lugano, Lugano, Switzerland. 6. Zürcher Höhenklinik, Wald-Faltigberg, Faltigberg-Wald, Switzerland. 7. Lungenpraxis Hirslanden Klinik Aarau, Aarau, Switzerland.
Abstract
BACKGROUND: longitudinal analyses of physical activity (PA) and arterial stiffness in populations of older adults are scarce. We examined associations between long-term change of PA and arterial stiffness in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). METHODS: we assessed PA in SAPALDIA 2 (2001-03) and SAPALDIA 3 (2010-11) using a short questionnaire with a cut-off of at least 150 min of moderate-to-vigorous PA per week for sufficient activity. Arterial stiffness was measured oscillometrically by means of the brachial-ankle pulse wave velocity (baPWV) in SAPALDIA 3. We used multivariable mixed linear regression models adjusted for several potential confounders in 2,605 persons aged 50-81. RESULTS: adjusted means of baPWV were significantly lower in persons with sufficient moderate-to-vigorous PA (i) in SAPALDIA 2 but not in SAPALDIA 3 (P = 0.048) and (ii) in both surveys (P = 0.001) compared with persons with insufficient activity in both surveys. There was a significant interaction between sex and the level of change in PA concerning baPWV (P = 0.03). The triples of parameter estimates describing the association between level of PA change and baPWV were not significantly different between the two sex-specific models (P = 0.07). CONCLUSIONS: keeping up or adopting a physically active lifestyle was associated with lower arterial stiffness in older adults after a follow-up of almost a decade. Increasing the proportion of older adults adhering to PA recommendations incorporating also vigorous PA may have a considerable impact on vascular health at older age and may contribute to healthy ageing in general.
BACKGROUND: longitudinal analyses of physical activity (PA) and arterial stiffness in populations of older adults are scarce. We examined associations between long-term change of PA and arterial stiffness in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). METHODS: we assessed PA in SAPALDIA 2 (2001-03) and SAPALDIA 3 (2010-11) using a short questionnaire with a cut-off of at least 150 min of moderate-to-vigorous PA per week for sufficient activity. Arterial stiffness was measured oscillometrically by means of the brachial-ankle pulse wave velocity (baPWV) in SAPALDIA 3. We used multivariable mixed linear regression models adjusted for several potential confounders in 2,605 persons aged 50-81. RESULTS: adjusted means of baPWV were significantly lower in persons with sufficient moderate-to-vigorous PA (i) in SAPALDIA 2 but not in SAPALDIA 3 (P = 0.048) and (ii) in both surveys (P = 0.001) compared with persons with insufficient activity in both surveys. There was a significant interaction between sex and the level of change in PA concerning baPWV (P = 0.03). The triples of parameter estimates describing the association between level of PA change and baPWV were not significantly different between the two sex-specific models (P = 0.07). CONCLUSIONS: keeping up or adopting a physically active lifestyle was associated with lower arterial stiffness in older adults after a follow-up of almost a decade. Increasing the proportion of older adults adhering to PA recommendations incorporating also vigorous PA may have a considerable impact on vascular health at older age and may contribute to healthy ageing in general.
Authors: Veronica Onete; Ronald M Henry; Simone J S Sep; Annemarie Koster; Carla J van der Kallen; Pieter C Dagnelie; Nicolaas Schaper; Sebastian Köhler; Koen Reesink; Coen D A Stehouwer; Miranda T Schram Journal: J Psychiatry Neurosci Date: 2017-10-12 Impact factor: 6.186
Authors: Sara Ahmadi-Abhari; Severine Sabia; Martin J Shipley; Mika Kivimäki; Archana Singh-Manoux; Adam Tabak; Carmel McEniery; Ian B Wilkinson; Eric J Brunner Journal: J Am Heart Assoc Date: 2017-08-07 Impact factor: 5.501
Authors: Simon Endes; Seraina Caviezel; Emmanuel Schaffner; Julia Dratva; Christian Schindler; Nino Künzli; Martin Bachler; Siegfried Wassertheurer; Nicole Probst-Hensch; Arno Schmidt-Trucksäss Journal: PLoS One Date: 2016-09-29 Impact factor: 3.240