Literature DB >> 26764288

Six-month Follow-up of Cognitive Impairment and Depressive Symptoms in Late-onset Depression.

M M C Wong1, C F Chan2, S W Li2, Y M Lau2.   

Abstract

OBJECTIVE: To assess cognitive performance in elderly depressed patients following treatment for 6 months. Remission rate of depression after 6 months of treatment was calculated.
METHODS: The study was performed in a consecutive group of patients aged ≥ 65 years with late-onset depression. Severity of depression was assessed by the Hamilton Depression Scale, cognitive performance by the Hong Kong Montreal Cognitive Assessment, and functional level by the Instrumental Activities of Daily Living Scale.
RESULTS: A total of 52 patients were recruited. In all, 28 (53.8%) were found to have cognitive impairment at baseline and 8 (28.6%) of them had improvement after 6 months. This cognitively impaired group was older and had a lower Instrumental Activities of Daily Living Scale score. The remission rate of depression was 61.5%.
CONCLUSIONS: Cognitive impairment constituted a stable feature in a considerable number of elderly patients with depression. About two-thirds of patients achieved remission of depression after 6 months of treatment.

Entities:  

Keywords:  Age of onset; Depression; Mild cognitive impairment

Mesh:

Substances:

Year:  2015        PMID: 26764288

Source DB:  PubMed          Journal:  East Asian Arch Psychiatry        ISSN: 2078-9947


  5 in total

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Journal:  Sci Rep       Date:  2016-11-25       Impact factor: 4.379

2.  Cognitive deficits in older adults with mild cognitive impairment in a two-year follow-up study.

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Journal:  Int J Biol Sci       Date:  2018-08-10       Impact factor: 6.580

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5.  Happiness, depression, physical activity and cognition among the middle and old-aged population in China: a conditional process analysis.

Authors:  Xiaojuan Shi; Xiaoxue He; Degong Pan; Hui Qiao; Jiangping Li
Journal:  PeerJ       Date:  2022-06-28       Impact factor: 3.061

  5 in total

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