S Fernández-Barrés1,2, D Romaguera1,3,4, D Valvi1,5,6,7, D Martínez1,5,6, J Vioque5,8, E M Navarrete-Muñoz5,8, P Amiano5,9, S Gonzalez-Palacios5,8, M Guxens1,5,6,10, E Pereda11, I Riaño5,12, A Tardón5,13, C Iñiguez14, V Arija2, J Sunyer1,5,6,15, M Vrijheid1,5,6,15. 1. Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. 2. Nutrition and Mental Health Group, Universitat Rovira I Virgili (URV), Reus, Spain. 3. Instituto de Investigación Sanitaria de Palma (IdISPa), Hospital Universitari Son Espases, Palma de Mallorca, Spain. 4. CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Madrid, Spain. 5. CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. 6. Universitat Pompeu Fabra (UPF), Barcelona, Spain. 7. Harvard T.H. Chan School of Public Health, Boston, MA, USA. 8. Universidad Miguel Hernandez, Alicante, Spain. 9. Public Health Division of Gipuzkoa, BioDonostia Research Institute, San Sebastián, Spain. 10. Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, The Netherlands. 11. Facultad de Psicología, Universidad del País Vasco-Euskal Herriko Unibertsitatea (UPV-EHU), Bizkaia, Spain. 12. Hospital San Agustín, SESPA, Asturias, Spain. 13. Universidad de Oviedo, Asturias, Spain. 14. FISABIO - Universitat Jaume I - Universitat de València Epidemiology and Environmental Health Joint Research Unit, Valencia, Spain. 15. Institut Hospital del Mar d'Investigacions Mèdiques-Parc de Salut Mar, Barcelona, Spain.
Abstract
BACKGROUND: Animal models have suggested that maternal diet quality may reduce offspring obesity risk regardless of maternal body weight; however, evidence from human studies is scarce. OBJECTIVE: The aim of this study was to evaluate associations between adherence to the Mediterranean diet (MD) during pregnancy and childhood overweight and abdominal obesity risk at 4 years of age. METHODS: We analysed 1827 mother-child pairs from the Spanish 'Infancia y Medio Ambiente' cohort study, recruited between 2003 and 2008. Diet was assessed during pregnancy using a food frequency questionnaire and MD adherence by the relative Mediterranean diet score (rMED). Overweight (including obesity) was defined as an age-specific and sex-specific body mass index ≥85th percentile (World Health Organization referent), and abdominal obesity as a waist circumference (WC) >90th percentile. Multivariate adjusted linear and logistic regression models were used to evaluate associations between pregnancy rMED and offspring overweight and abdominal obesity. RESULT: There was no association between rMED and body mass index z-score, whereas there was a significant association between higher adherence to MD and lower WC (β of high vs. low rMED: -0.62 cm; 95% confidence interval: -1.10, -0.14 cm, P for trend = 0.009). CONCLUSION: Pregnancy adherence to the MD was not associated with childhood overweight risk, but it was associated with lower WC, a marker of abdominal obesity.
BACKGROUND: Animal models have suggested that maternal diet quality may reduce offspring obesity risk regardless of maternal body weight; however, evidence from human studies is scarce. OBJECTIVE: The aim of this study was to evaluate associations between adherence to the Mediterranean diet (MD) during pregnancy and childhood overweight and abdominal obesity risk at 4 years of age. METHODS: We analysed 1827 mother-child pairs from the Spanish 'Infancia y Medio Ambiente' cohort study, recruited between 2003 and 2008. Diet was assessed during pregnancy using a food frequency questionnaire and MD adherence by the relative Mediterranean diet score (rMED). Overweight (including obesity) was defined as an age-specific and sex-specific body mass index ≥85th percentile (World Health Organization referent), and abdominal obesity as a waist circumference (WC) >90th percentile. Multivariate adjusted linear and logistic regression models were used to evaluate associations between pregnancy rMED and offspring overweight and abdominal obesity. RESULT: There was no association between rMED and body mass index z-score, whereas there was a significant association between higher adherence to MD and lower WC (β of high vs. low rMED: -0.62 cm; 95% confidence interval: -1.10, -0.14 cm, P for trend = 0.009). CONCLUSION: Pregnancy adherence to the MD was not associated with childhood overweight risk, but it was associated with lower WC, a marker of abdominal obesity.
Authors: S Sen; S L Rifas-Shiman; N Shivappa; M D Wirth; J R Hebert; D R Gold; M W Gillman; E Oken Journal: Pediatr Obes Date: 2017-05-10 Impact factor: 4.000
Authors: L Chatzi; S L Rifas-Shiman; V Georgiou; K E Joung; S Koinaki; G Chalkiadaki; A Margioris; K Sarri; M Vassilaki; M Vafeiadi; M Kogevinas; C Mantzoros; M W Gillman; E Oken Journal: Pediatr Obes Date: 2017-02-03 Impact factor: 4.000
Authors: Carmen Monthé-Drèze; Sheryl L Rifas-Shiman; Izzuddin M Aris; Nitin Shivappa; James R Hebert; Sarbattama Sen; Emily Oken Journal: Am J Clin Nutr Date: 2021-04-06 Impact factor: 7.045