Cameron J Lacey1,2, Michael R Salzberg1, Wendyl J D'Souza2. 1. Department of Psychiatry, St. Vincent's Hospital Melbourne, The University of Melbourne, Melbourne, Victoria, Australia. 2. Department of Medicine, St. Vincent's Hospital Melbourne, The University of Melbourne, Melbourne, Victoria, Australia.
Abstract
OBJECTIVE: To model the factors associated with depression in a community sample of people with epilepsy. The factors investigated were derived from proposed risk factors for depression from patients with epilepsy, other chronic illness, and the general population. METHODS: Multivariate analysis using general linear regression models of factors associated with depression in the Tasmanian Epilepsy Register Mood Study (TERMS), a cross-sectional community sample of 440 patients with epilepsy. RESULTS: A model with acceptable fit was created that explained 66% of the variance of depression. Associated factors included in this model were neuroticism, physical functioning, social support, past history of depression, and stressful life events. SIGNIFICANCE: In this cross-sectional study designed specifically to investigate depression in epilepsy, we showed that general risk factors for depression in other illness and in the general population are also important in patients with epilepsy, with little support for disease-related risk factors. Wiley Periodicals, Inc.
OBJECTIVE: To model the factors associated with depression in a community sample of people with epilepsy. The factors investigated were derived from proposed risk factors for depression from patients with epilepsy, other chronic illness, and the general population. METHODS: Multivariate analysis using general linear regression models of factors associated with depression in the Tasmanian Epilepsy Register Mood Study (TERMS), a cross-sectional community sample of 440 patients with epilepsy. RESULTS: A model with acceptable fit was created that explained 66% of the variance of depression. Associated factors included in this model were neuroticism, physical functioning, social support, past history of depression, and stressful life events. SIGNIFICANCE: In this cross-sectional study designed specifically to investigate depression in epilepsy, we showed that general risk factors for depression in other illness and in the general population are also important in patients with epilepsy, with little support for disease-related risk factors. Wiley Periodicals, Inc.
Authors: Charlene N Rivera Bonet; Gyujoon Hwang; Bruce Hermann; Aaron F Struck; Cole J Cook; Veena A Nair; Jedidiah Mathis; Linda Allen; Dace N Almane; Karina Arkush; Rasmus Birn; Lisa L Conant; Edgar A DeYoe; Elizabeth Felton; Rama Maganti; Andrew Nencka; Manoj Raghavan; Umang Shah; Veronica N Sosa; Candida Ustine; Vivek Prabhakaran; Jeffrey R Binder; Mary E Meyerand Journal: Epilepsy Behav Date: 2020-06-14 Impact factor: 2.937