Literature DB >> 26759436

Unusual neurological presentation of Fusobacterium necrophorum disease.

Nasrean Haddad1, Trefor Morris2, Rishi Dhillon3, Frances Gibbon1.   

Abstract

A 2-year-old girl presented to hospital, with reduced consciousness and fever. She had a 4-week history of fever treated with two courses of amoxicillin for tonsillitis diagnosed in primary care. Neuroimaging revealed multiple cerebral abscesses and subdural empyema. Pus aspirated from the intracranial collections grew Fusobacterium necrophorum and meropenem was started. Following neurosurgery, the patient continued to be agitated with fluctuating fever. She underwent close monitoring with regular neuroimaging. To control the progression of intracranial infection, she underwent three separate neurosurgical procedures following which she made a good recovery. This case demonstrates how an organism rarely associated with childhood illnesses presented atypically and progressed into a complex potentially fatal intracranial infection requiring a high degree of neurosurgical intervention. Awareness of this organism is important. The combination of source control together with appropriate antibiotic use was crucial in controlling the infection. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 26759436      PMCID: PMC4716438          DOI: 10.1136/bcr-2015-210710

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

1.  Prevalence of Fusobacterium necrophorum in persistent sore throat samples.

Authors:  S L Price; S Hardy; P Gale; G P Basten
Journal:  Br J Biomed Sci       Date:  2011       Impact factor: 3.829

2.  Prevalence of Fusobacterium necrophorum and other upper respiratory tract pathogens isolated from throat swabs.

Authors:  A Batty; M W D Wren
Journal:  Br J Biomed Sci       Date:  2005       Impact factor: 3.829

Review 3.  Human infections with Fusobacterium necrophorum.

Authors:  Jon S Brazier
Journal:  Anaerobe       Date:  2005-12-22       Impact factor: 3.331

4.  Expand the pharyngitis paradigm for adolescents and young adults.

Authors:  Robert M Centor
Journal:  Ann Intern Med       Date:  2009-12-01       Impact factor: 25.391

Review 5.  Fusobacterium necrophorum middle ear infections in children and related complications: report of 25 cases and literature review.

Authors:  Alban Le Monnier; Anne Jamet; Etienne Carbonnelle; Gwladys Barthod; Kaoutar Moumile; Fabrice Lesage; Jean-Ralph Zahar; Yves Mannach; Patrick Berche; Vincent Couloigner
Journal:  Pediatr Infect Dis J       Date:  2008-07       Impact factor: 2.129

6.  Fusobacterium necrophorum mastoiditis in children - emerging pathogen in an old disease.

Authors:  Havatzelet Yarden-Bilavsky; Eyal Raveh; Gilat Livni; Oded Scheuerman; Jacob Amir; Efraim Bilavsky
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2012-10-25       Impact factor: 1.675

7.  A six-month audit of the isolation of Fusobacterium necrophorum from patients with sore throat in a district general hospital.

Authors:  J A Amess; W O'Neill; C Ni Giollariabhaigh; J K Dytrych
Journal:  Br J Biomed Sci       Date:  2007       Impact factor: 3.829

8.  Fusobacterium necrophorum, an emerging pathogen of otogenic and paranasal infections?

Authors:  D Creemers-Schild; F Gronthoud; L Spanjaard; L G Visser; C N M Brouwer; E J Kuijper
Journal:  New Microbes New Infect       Date:  2014-03-25
  8 in total

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