Literature DB >> 26758443

CORR Insights(®): Does Sclerostin Depletion Stimulate Fracture Healing in a Mouse Model?

Nilsson Holguin1.   

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Year:  2016        PMID： 26758443      PMCID： PMC4814410          DOI： 10.1007/s11999-016-4697-3

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN： 0009-921X            Impact factor:   4.176


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  13 in total

1.  Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats.

Authors:  Xiaodong Li; Kelly S Warmington; Qing-Tian Niu; Franklin J Asuncion; Mauricio Barrero; Mario Grisanti; Denise Dwyer; Brian Stouch; Theingi M Thway; Marina Stolina; Michael S Ominsky; Paul J Kostenuik; William S Simonet; Chris Paszty; Hua Zhu Ke
Journal:  J Bone Miner Res       Date:  2010-07-16       Impact factor: 6.741

2.  Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength.

Authors:  Michael S Ominsky; Fay Vlasseros; Jacquelin Jolette; Susan Y Smith; Brian Stouch; George Doellgast; Jianhua Gong; Yongming Gao; Jin Cao; Kevin Graham; Barbara Tipton; Jill Cai; Rohini Deshpande; Lei Zhou; Michael D Hale; Daniel J Lightwood; Alistair J Henry; Andrew G Popplewell; Adrian R Moore; Martyn K Robinson; David L Lacey; W Scott Simonet; Chris Paszty
Journal:  J Bone Miner Res       Date:  2010-05       Impact factor: 6.741

3.  Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue.

Authors:  Meina Wang; Dezhi Tang; Bing Shu; Baoli Wang; Hongting Jin; Suyang Hao; Karen A Dresser; Jie Shen; Hee-Jeong Im; Erik R Sampson; Paul T Rubery; Michael J Zuscik; Edward M Schwarz; Regis J O'Keefe; Yongjun Wang; Di Chen
Journal:  Arthritis Rheum       Date:  2012-08

4.  Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody.

Authors:  Desmond Padhi; Graham Jang; Brian Stouch; Liang Fang; Edward Posvar
Journal:  J Bone Miner Res       Date:  2011-01       Impact factor: 6.741

5.  Romosozumab in postmenopausal women with low bone mineral density.

Authors:  Michael R McClung; Andreas Grauer; Steven Boonen; Michael A Bolognese; Jacques P Brown; Adolfo Diez-Perez; Bente L Langdahl; Jean-Yves Reginster; Jose R Zanchetta; Scott M Wasserman; Leonid Katz; Judy Maddox; Yu-Ching Yang; Cesar Libanati; Henry G Bone
Journal:  N Engl J Med       Date:  2014-01-01       Impact factor: 91.245

6.  The Effect of Discontinuing Treatment With Blosozumab: Follow-up Results of a Phase 2 Randomized Clinical Trial in Postmenopausal Women With Low Bone Mineral Density.

Authors:  Christopher P Recknor; Robert R Recker; Charles T Benson; Deborah A Robins; Alan Y Chiang; Jahangir Alam; Leijun Hu; Toshio Matsumoto; Hideaki Sowa; John H Sloan; Robert J Konrad; Bruce H Mitlak; Adrien A Sipos
Journal:  J Bone Miner Res       Date:  2015-06-11       Impact factor: 6.741

7.  Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones.

Authors:  Michael S Ominsky; Chaoyang Li; Xiaodong Li; Hong L Tan; Edward Lee; Mauricio Barrero; Franklin J Asuncion; Denise Dwyer; Chun-Ya Han; Fay Vlasseros; Rana Samadfam; Jacquelin Jolette; Susan Y Smith; Marina Stolina; David L Lacey; William S Simonet; Chris Paszty; Gang Li; Hua Z Ke
Journal:  J Bone Miner Res       Date:  2011-05       Impact factor: 6.741

8.  Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction.

Authors:  Mei Zhu; Mo Chen; Michael Zuscik; Qiuqian Wu; Yong-Jun Wang; Randy N Rosier; Regis J O'Keefe; Di Chen
Journal:  Arthritis Rheum       Date:  2008-07

9.  Modulation of Wnt signaling influences fracture repair.

Authors:  David E Komatsu; Michelle N Mary; Robert Jason Schroeder; Alex G Robling; Charles H Turner; Stuart J Warden
Journal:  J Orthop Res       Date:  2010-07       Impact factor: 3.494

10.  Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength.

Authors:  Xiaodong Li; Michael S Ominsky; Qing-Tian Niu; Ning Sun; Betsy Daugherty; Diane D'Agostin; Carole Kurahara; Yongming Gao; Jin Cao; Jianhua Gong; Frank Asuncion; Mauricio Barrero; Kelly Warmington; Denise Dwyer; Marina Stolina; Sean Morony; Ildiko Sarosi; Paul J Kostenuik; David L Lacey; W Scott Simonet; Hua Zhu Ke; Chris Paszty
Journal:  J Bone Miner Res       Date:  2008-06       Impact factor: 6.741
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  1 in total

1.  In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin Signaling.

Authors:  Nilsson Holguin; Matthew J Silva
Journal:  Sci Rep       Date:  2018-07-25       Impact factor: 4.379
  1 in total

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