Literature DB >> 26758427

Circulating serum levels of angiopoietin-1 and angiopoietin-2 in nasopharynx and larynx carcinoma patients.

Murat Emin Güveli1, Derya Duranyildiz2, Ahmet Karadeniz3, Elif Bilgin3, Murat Serilmez3, Hilal Oguz Soydinc3, Vildan Yasasever3.   

Abstract

We aimed to determine the serum levels of angiogenic factors, namely angiopoietins, in nasopharyngeal and laryngeal carcinoma patients. We also aimed to seek the relation of these molecules with tumor grade and their utility as diagnostic biomarkers. We evaluated angiopoietin 1 and 2 levels innasopharynx and larynx cancer patients before treatment. Angiopoietin 2 levels were significantly elevated in larynx carcinoma patients and tended to be elevated in nasopharynx cancer patients compared with healthy controls. However, angiopoietin 1 levels were similar in cancer patients and controls. Angiopoietin 1 levels were significantly higher in nasopharyngeal cancer patients with advanced stages compared to earlier stages. On the other hand, angiopoietin 2 levels were similar in advanced and earlier stage cancer patients.

Entities:  

Keywords:  Angiopoietins; Larynx cancer; Nasopharynx cancer

Mesh：

Substances：

Year:  2016        PMID： 26758427     DOI： 10.1007/s13277-015-4777-0

Source DB:  PubMed          Journal:  Tumour Biol        ISSN： 1010-4283


  20 in total

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2.  Clinical and prognostic significance of circulating levels of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma.

Authors:  Roberto Carmagnani Pestana; Manal M Hassan; Reham Abdel-Wahab; Yehia I Abugabal; Lauren M Girard; Donghui Li; Ping Chang; Kanwal Raghav; Jeff Morris; Robert A Wolff; Asif Rashid; Hesham M Amin; Ahmed Kaseb
Journal:  Oncotarget       Date:  2018-12-28
  2 in total

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