Literature DB >> 26757778

Cytisine-type alkaloids and flavonoids from the rhizomes of Sophora tonkinensis.

Qi-Ming Pan1, Gui-Jie Zhang2, Ri-Zhen Huang1, Ying-Ming Pan1, Heng-Shan Wang1, Dong Liang1.   

Abstract

A new cytisine-type alkaloid, (-)-N-hexanoylcytisine (1), and a new isoflavan, (3S, 4R)-4-hydroxy-7,4'-dimethoxyisoflavan 3'-O-β-d-glucopyranoside (2), along with 10 known compounds, were isolated from the rhizomes of Sophora tonkinensis. Their structures were determined by spectroscopic methods, chemical evidence, and ECD data analysis. All of the isolates were evaluated for their cytotoxic activities against four human tumor cell lines.

Entities:  

Keywords:  Leguminosae; Sophora tonkinensis; cytisine-type alkaloid; cytotoxic activity; isoflavan

Mesh:

Substances:

Year:  2016        PMID: 26757778     DOI: 10.1080/10286020.2015.1131680

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  6 in total

1.  Three new alkaloids from the roots of Sophora tonkinensis.

Authors:  Chun Wu; Lijun He; Xue Yi; Juan Qin; Yaolan Li; Yubo Zhang; Guocai Wang
Journal:  J Nat Med       Date:  2019-04-26       Impact factor: 2.343

Review 2.  Biological Activities and Secondary Metabolites from Sophora tonkinensis and Its Endophytic Fungi.

Authors:  Jia-Jun Liang; Pan-Pan Zhang; Wei Zhang; Da Song; Xin Wei; Xin Yin; Yong-Qiang Zhou; Xiang Pu; Ying Zhou
Journal:  Molecules       Date:  2022-08-29       Impact factor: 4.927

3.  Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of Flavonoid Profiles by HPLC-PAD.

Authors:  Mengyang Hou; Wenzhong Hu; Zhilong Xiu; Aili Jiang; Lei Men; Kexin Hao; Xingsheng Sun; Duo Cao
Journal:  Molecules       Date:  2019-09-03       Impact factor: 4.411

4.  Cytisine-Pterocarpan-Derived Compounds: Biomimetic Synthesis and Apoptosis-Inducing Activity in Human Breast Cancer Cells.

Authors:  Ting-Ting Peng; Xuan-Rong Sun; Ren-Hao Liu; Lu-Xia Hua; Dong-Ping Cheng; Bin Mao; Xing-Nuo Li
Journal:  Molecules       Date:  2018-11-22       Impact factor: 4.411

5.  Integrated transcriptome and small RNA sequencing analyses reveal a drought stress response network in Sophora tonkinensis.

Authors:  Ying Liang; Kunhua Wei; Fan Wei; Shuangshuang Qin; Chuanhua Deng; Yang Lin; Mingjie Li; Li Gu; Guili Wei; Jianhua Miao; Zhongyi Zhang
Journal:  BMC Plant Biol       Date:  2021-12-02       Impact factor: 4.215

6.  Preparative Separation of Alkaloids from Stem of Euchresta tubulosa Dunn. by High-Speed Counter-Current Chromatography Using Stepwise Elution.

Authors:  Weixin Li; Huan Wang; Aiwen Dong
Journal:  Molecules       Date:  2019-12-16       Impact factor: 4.411

  6 in total

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