Literature DB >> 26756377

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas.

Yu Zhou1, Jiang Wang1, Zhanni Gu1, Shuni Wang1, Wei Zhu1, José Luis Aceña2,3, Vadim A Soloshonok2,4, Kunisuke Izawa5, Hong Liu1.   

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Year:  2016        PMID： 26756377     DOI： 10.1021/acs.chemrev.5b00392

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  190 in total

1.  Catalytic, Enantioselective 1,2-Difluorination of Cinnamamides.

Authors:  Moriana K Haj; Steven M Banik; Eric N Jacobsen
Journal:  Org Lett       Date:  2019-04-09       Impact factor: 6.005

2.  η 2 Coordination of Electron-Deficient Arenes with Group 6 Dearomatization Agents.

Authors:  Jacob A Smith; Spenser R Simpson; Karl S Westendorff; Justin Weatherford-Pratt; Jeffery T Myers; Justin H Wilde; Diane A Dickie; W Dean Harman
Journal:  Organometallics       Date:  2020-06-25       Impact factor: 3.876

3.  Organocatalytic Stereoselective Synthesis of Fluorinated 3,3'-Linked Bisoxindoles.

Authors:  Max Moskowitz; Kaluvu Balaraman; Christian Wolf
Journal:  J Org Chem       Date:  2018-01-22       Impact factor: 4.354

4.  Radical Chlorodifluoromethylation: Providing a Motif for (Hetero)arene Diversification.

Authors:  Rory C McAtee; Joel W Beatty; Christopher C McAtee; Corey R J Stephenson
Journal:  Org Lett       Date:  2018-06-01       Impact factor: 6.005

5.  Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.

Authors:  Manasa Ravindra; Mike R Wilson; Nian Tong; Carrie O'Connor; Mohammad Karim; Lisa Polin; Adrianne Wallace-Povirk; Kathryn White; Juiwanna Kushner; Zhanjun Hou; Larry H Matherly; Aleem Gangjee
Journal:  J Med Chem       Date:  2018-04-27       Impact factor: 7.446

6.  Metal-Free and User-Friendly Regioselective Hydroxyfluorination of Olefins.

Authors:  Daniel M Sedgwick; Inés López; Raquel Román; Nanako Kobayashi; Otome E Okoromoba; Bo Xu; Gerald B Hammond; Pablo Barrio; Santos Fustero
Journal:  Org Lett       Date:  2018-04-06       Impact factor: 6.005

7.  Selective C-F Functionalization of Unactivated Trifluoromethylarenes.

Authors:  David B Vogt; Ciaran P Seath; Hengbin Wang; Nathan T Jui
Journal:  J Am Chem Soc       Date:  2019-08-09       Impact factor: 15.419

8.  Chemoselective fluorination and chemoinformatic analysis of griseofulvin: Natural vs fluorinated fungal metabolites.

Authors:  Noemi D Paguigan; Mohammed H Al-Huniti; Huzefa A Raja; Austin Czarnecki; Joanna E Burdette; Mariana González-Medina; José L Medina-Franco; Stephen J Polyak; Cedric J Pearce; Mitchell P Croatt; Nicholas H Oberlies
Journal:  Bioorg Med Chem       Date:  2017-07-28       Impact factor: 3.641

9.  Physical properties, ligand substitution reactions, and biological activity of Co(iii)-Schiff base complexes.

Authors:  A Paden King; Hendryck A Gellineau; Samantha N MacMillan; Justin J Wilson
Journal:  Dalton Trans       Date:  2019-05-07       Impact factor: 4.390

10.  Stereoselective Synthesis of 3,3'-Bisindolines by Organocatalytic Michael Additions of Fluorooxindole Enolates to Isatylidene Malononitriles in Aqueous Solution.

Authors:  Kaluvu Balaraman; Ransheng Ding; Christian Wolf
Journal:  Adv Synth Catal       Date:  2017-09-22       Impact factor: 5.837
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