Literature DB >> 26755189

Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding.

Sofia Nunes-Silva1,2,3,4, Sébastien Dechavanne1,2,3,4, Azizath Moussiliou4,5,6, Natalia Pstrąg1,2,3,4, Jean-Philippe Semblat1,2,3,4, Stéphane Gangnard1,2,3,4, Nicaise Tuikue-Ndam4,5,6, Philippe Deloron4,5,6, Arnaud Chêne1,2,3,4, Benoît Gamain7,8,9,10.   

Abstract

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Year:  2016        PMID: 26755189      PMCID: PMC4710028          DOI: 10.1186/s12936-015-1061-0

Source DB:  PubMed          Journal:  Malar J        ISSN: 1475-2875            Impact factor:   2.979


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Erratum to: Malar J (2015) 14:493 DOI 10.1186/s12936-015-1008-5

After publication of the original article [1], it was noticed that Fig. 1 was inadvertently altered during production. While ensuring the Figure was suitable for inclusion and conformed to style guidelines, Fig. 1b was mistakenly cropped in a way that reduced the effectiveness of the Figure. Figure 1 has now been replaced with the correct version in the original article, and is published correctly below.
Fig. 1

Recombinant proteins expressed in HEK293 cells. a Representation of IT4-VAR19 domain organization and sequence limits of the full-length IT4-VAR19 and the recombinant IT4-VAR19 domains studied (VAR19-NTS-DBLɣ6 and CIDRα1.1). IT4-VAR19 is composed of five Duffy-binding-like domains (shown in green), two cysteine-rich interdomain regions (shown in red), a transmembrane segment and an acidic C terminus sequence (ATS, shown in blue). b SDS-PAGE under reducing and non-reducing conditions of purified VAR19-NTS-DBLɣ6 and CIDRα1.1. c SDS-PAGE under reducing and non-reducing conditions of purified recombinant EPCR proteins (His tagged EPCRH and His/FLAG tagged)

Recombinant proteins expressed in HEK293 cells. a Representation of IT4-VAR19 domain organization and sequence limits of the full-length IT4-VAR19 and the recombinant IT4-VAR19 domains studied (VAR19-NTS-DBLɣ6 and CIDRα1.1). IT4-VAR19 is composed of five Duffy-binding-like domains (shown in green), two cysteine-rich interdomain regions (shown in red), a transmembrane segment and an acidic C terminus sequence (ATS, shown in blue). b SDS-PAGE under reducing and non-reducing conditions of purified VAR19-NTS-DBLɣ6 and CIDRα1.1. c SDS-PAGE under reducing and non-reducing conditions of purified recombinant EPCR proteins (His tagged EPCRH and His/FLAG tagged) Additionally, Additional file 2 was incorrectly supplied as a duplicate of Additional file 1 during the proofing process. The original article has been updated with the correct file for Additional file 2, ‘Antibodies raised against VAR19-NTS-DBLγ6 inhibit its interaction with EPCR’, which also appears correctly in this erratum.
  1 in total

1.  Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding.

Authors:  Sofia Nunes-Silva; Sébastien Dechavanne; Azizath Moussiliou; Natalia Pstrąg; Jean-Philippe Semblat; Stéphane Gangnard; Nicaise Tuikue-Ndam; Philippe Deloron; Arnaud Chêne; Benoît Gamain
Journal:  Malar J       Date:  2015-12-08       Impact factor: 2.979

  1 in total

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