Literature DB >> 26754479

Assessment of Cognitive Outcome Measures in Teenagers with 15q13.3 Microdeletion Syndrome.

Emeline Crutcher1,2,3, May Ali2,3, John Harrison4, Judit Sovago5, Baltazar Gomez-Mancilla5,6, Christian P Schaaf7,8,9.   

Abstract

15q13.3 microdeletion syndrome causes a spectrum of cognitive disorders, including intellectual disability and autism. We aimed to determine if any or all of three cognitive testing systems (the KiTAP, CogState, and Stanford-Binet) are suitable for assessment of cognitive function in affected individuals. These three tests were administered to ten individuals with 15q13.3 microdeletion syndrome (14-18 years of age), and the results were analyzed to determine feasibility of use, potential for improvement, and internal consistency. It was determined that the KiTAP, CogState, and Stanford-Binet are valid tests of cognitive function in 15q13.3 microdeletion patients. Therefore, these tests may be considered for use as objective outcome measures in future clinical trials, assessing change in cognitive function over a period of pharmacological treatment.

Entities:  

Keywords:  Autism; Cognitive function; Cognitive tests; Intellectual disability; Neuropsychiatric disease

Mesh：

Year:  2016        PMID： 26754479      PMCID： PMC5362964          DOI： 10.1007/s10803-015-2694-0

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN： 0162-3257


  17 in total

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2.  Clinical utility gene card for: 15q13.3 microdeletion syndrome.

Authors:  Maria Tropeano; Joris Andrieux; Evangelos Vassos; David A Collier
Journal:  Eur J Hum Genet       Date:  2014-05-14       Impact factor: 4.246

Review 3.  Evidence-based assessment of autism spectrum disorders in children and adolescents.

Authors:  Sally Ozonoff; Beth L Goodlin-Jones; Marjorie Solomon
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4.  Effects of methylphenidate on intelligence and attention components in boys with attention-deficit/hyperactivity disorder.

Authors:  Susanne Hellwig-Brida; Monika Daseking; Ferdinand Keller; Franz Petermann; Lutz Goldbeck
Journal:  J Child Adolesc Psychopharmacol       Date:  2011-06       Impact factor: 2.576

Review 5.  The human clinical phenotypes of altered CHRNA7 copy number.

Authors:  Madelyn A Gillentine; Christian P Schaaf
Journal:  Biochem Pharmacol       Date:  2015-06-18       Impact factor: 5.858

6.  Summer treatment program for children with attention deficit hyperactivity disorder: Japanese experience in 5 years.

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7.  Predictive validity of attentional functions in differentiating children with and without ADHD: a componential analysis.

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Journal:  Dev Med Child Neurol       Date:  2010-01-05       Impact factor: 5.449

Review 8.  Outcome measures for clinical drug trials in autism.

Authors:  Michael G Aman; Sherie Novotny; Carole Samango-Sprouse; Luc Lecavalier; Elizabeth Leonard; Kenneth D Gadow; Bryan H King; Deborah A Pearson; Morton Ann Gernsbacher; Michael Chez
Journal:  CNS Spectr       Date:  2004-01       Impact factor: 3.790

9.  A randomized, double-blind, placebo-controlled crossover study of α4β 2* nicotinic acetylcholine receptor agonist AZD1446 (TC-6683) in adults with attention-deficit/hyperactivity disorder.

Authors:  Aurelija Jucaite; John Öhd; Alexandra S Potter; Judith Jaeger; Pär Karlsson; Kristin Hannesdottir; Emma Boström; Paul A Newhouse; Björn Paulsson
Journal:  Psychopharmacology (Berl)       Date:  2013-05-03       Impact factor: 4.530

Review 10.  Delineating the 15q13.3 microdeletion phenotype: a case series and comprehensive review of the literature.

Authors:  Chelsea Lowther; Gregory Costain; Dimitri J Stavropoulos; Rebecca Melvin; Candice K Silversides; Danielle M Andrade; Joyce So; Hanna Faghfoury; Anath C Lionel; Christian R Marshall; Stephen W Scherer; Anne S Bassett
Journal:  Genet Med       Date:  2014-07-31       Impact factor: 8.822
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  2 in total

1.  Brain Network Analysis of EEG Recordings Can Be Used to Assess Cognitive Function in Teenagers With 15q13.3 Microdeletion Syndrome.

Authors:  Tehila Stern; Emeline H Crutcher; John M McCarthy; May A Ali; Gil Issachar; Amir B Geva; Ziv Peremen; Christian P Schaaf
Journal:  Front Neurosci       Date:  2021-01-28       Impact factor: 4.677

2.  JAKE® Multimodal Data Capture System: Insights from an Observational Study of Autism Spectrum Disorder.

Authors:  Seth L Ness; Nikolay V Manyakov; Abigail Bangerter; David Lewin; Shyla Jagannatha; Matthew Boice; Andrew Skalkin; Geraldine Dawson; Yvette M Janvier; Matthew S Goodwin; Robert Hendren; Bennett Leventhal; Frederick Shic; Walter Cioccia; Gahan Pandina
Journal:  Front Neurosci       Date:  2017-09-26       Impact factor: 4.677
  2 in total

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