Literature DB >> 2675402

Endomyocardial biopsies after heart transplantation. The presence of immunoglobulin/immune complex deposits.

H J Schuurman1, F H Meyling, P L Wijngaard, A van der Meulen, P J Slootweg, G Jambroes.   

Abstract

A series of 221 endomyocardial biopsies (EMB), taken from 21 patients after heart transplantation, was analyzed for the presence of immunoglobulin/immune complex deposits. Data were correlated with histology (grading following Billingham) and cytoimmunologic monitoring (CIM) on blood samples (grading into negative, rejection, or infection, based on leukocyte morphology and T cell phenotype). IgM deposits and IgG/IgM complexes in blood capillaries around myocyte fibrils were found in 78 and 40 EMB, respectively. This feature was more prevalent in EMB with a histology of rejection (39 out of 52 biopsies).

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Year:  1989        PMID: 2675402     DOI: 10.1097/00007890-198909000-00017

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  1 in total

1.  Monitoring rejection after heart transplantation: cytoimmunological monitoring on blood cells and quantitative birefringence measurements on endomyocardial biopsy specimens.

Authors:  P L Wijngaard; J A Gimpel; H J Schuurman; A van der Meulen; F H Gmelig Meyling; G Jambroes
Journal:  J Clin Pathol       Date:  1990-02       Impact factor: 3.411

  1 in total

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