Literature DB >> 26753319

[Spina bifida aperta in a sheep lamb].

N Gutzwiller, M Hilbe, P Kircher, U Bleull.   

Abstract

The case report describes the symptoms and diagnostic methods of a spina bifida aperta in a new born lamb. The most relevant clinical findings were recumbency immediately after birth with normal consciousness and suckling reflexes, alterations of the skin and coat in the lumbosacral region as well as dysuria. The biochemical and haematological screening of the blood indicated no abnormalities. While the radiological examination of the spine showed no clear evidence of the cause of the clinical sings the ultrasound and computed tomography examination revealed an incomplete closure of the vertebral arch between the 4th lumbar and the 3rd sacral vertebrae. Additionally, a hernia with similar density to the spinal cord was present in the same region of the spine. Based on the findings the lamb was euthanized. The pathological examination confirmed the incomplete closure of the vertebral arch and moreover a myelomeningocele has been diagnosed. In the histopathological examination the white and grey matter were separated in the area of the macroscopic visible lesions. Due to non-specific clinical symptoms imagining diagnostics can be crucial to confirm the diagnosis of this rare syndrome.

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Year:  2015        PMID: 26753319     DOI: 10.17236/sat00004

Source DB:  PubMed          Journal:  Schweiz Arch Tierheilkd        ISSN: 0036-7281            Impact factor:   0.845


  1 in total

1.  Heritable spina bifida in sheep: A potential model for fetal repair of myelomeningocele.

Authors:  John W Steele; Sharon Bayliss; John Bayliss; Ying Linda Lin; Bogdan J Wlodarczyk; Robert M Cabrera; Yohannes G Asfaw; Thomas J Cummings; Richard H Finnell; Timothy M George
Journal:  J Pediatr Surg       Date:  2019-06-29       Impact factor: 2.545

  1 in total

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