| Literature DB >> 26750998 |
Xiaoyu Ren1, Haifeng Du1.
Abstract
A highly enantioselective hydrosilylation of 1,2-dicarbonyl compounds was successfully realized for the first time utilizing the combination of tricyclohexylphosphine and chiral alkenylborane derived in situ from diyne as a frustrated Lewis pair catalyst. A variety of optically active α-hydroxy ketones and esters were obtained in 52-98% yields with 86-99% ee's.Entities:
Year: 2016 PMID： 26750998 DOI： 10.1021/jacs.5b13104
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419