Literature DB >> 26749825

Antimicrobial Diterpenes from Azorella Species Against Gram-Positive Bacteria.

Viviana Donoso, Mitchell Bacho, Solange Núiñez, Juana Rovirosa, Aurelio San-Martin, Sergio Leiva.   

Abstract

The present study was aimed at evaluating the antibacterial activity of mulinane and azorellane diterpenes isolated from the Andean plants Azorella compacta and A. trifoliolata and semisynthetic derivatives against reference and multidrug-resistant strains. The results revealed that the semisynthetic compound 7-acetoxy-mulin-9,12-diene (5) exhibited antibacterial activity against reference and multidrug-resistant strains of Staphylococcus aureus and moderate antimycobacterial activity against Mycobacterium smegmatis ATCC 14468.

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Year:  2015        PMID: 26749825

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  1 in total

Review 1.  Mulinane- and Azorellane-Type Diterpenoids: A Systematic Review of Their Biosynthesis, Chemistry, and Pharmacology.

Authors:  Angel de Jesús Dzul-Beh; Andrés Humberto Uc-Cachón; Jorge Bórquez; Luis A Loyola; Luis Manuel Peña-Rodríguez; Gloria María Molina-Salinas
Journal:  Biomolecules       Date:  2020-09-17
  1 in total

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