Literature DB >> 26749262

An Approach for the Selective Detection of Nitric Oxide in Biological Systems: An in vitro and in vivo Perspective.

Neha Gupta1, Shahi Imam Reja1, Vandana Bhalla1, Muskan Gupta2, Gurcharan Kaur2, Manoj Kumar3.   

Abstract

A naphthalimide-based fluorescent probe, LyNP-NO, was designed and synthesized for the selective detection of exogenously and endogenously generated nitric oxide (NO) in C6 glial cells. In addition, LyNP-NO was also explored for monitoring endogenous NO levels in rat hippocampus at various tissue depths by stimulating the brain with N-methyl-d-aspartate (NMDA).
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Keywords:  biological activity; fluorescent probes; imaging agents; lysosomes; nitric oxide

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Year:  2016        PMID: 26749262     DOI: 10.1002/asia.201501333

Source DB:  PubMed          Journal:  Chem Asian J        ISSN: 1861-471X


  1 in total

1.  Theoretical Design of a Two-Photon Fluorescent Probe for Nitric Oxide with Enhanced Emission Induced by Photoninduced Electron Transfer.

Authors:  Yujin Zhang; Jiancai Leng; Wei Hu
Journal:  Sensors (Basel)       Date:  2018-04-25       Impact factor: 3.576

  1 in total

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