Literature DB >> 26748750

Dramatic Expansion of HSCs: New Possibilities for HSC Transplants?

Sarah Nikiforow1, Jerome Ritz2.   

Abstract

The identification of mechanisms that regulate stem cell renewal has led to the development of innovative approaches to expand hematopoietic stem cells ex vivo. One approach reported by Wagner et al. (2016) in this issue of Cell Stem Cell has demonstrated dramatic expansion of umbilical cord blood stem cells that promote rapid engraftment while maintaining capacity for long-term hematopoiesis.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 26748750     DOI: 10.1016/j.stem.2015.12.011

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  9 in total

1.  Multilineage readout after HSC expansion - erythrocytes matter.

Authors:  Nicole Mende; Susann Rahmig; Claudia Waskow
Journal:  Cell Cycle       Date:  2016       Impact factor: 4.534

Review 2.  Engineered Tissue Models to Replicate Dynamic Interactions within the Hematopoietic Stem Cell Niche.

Authors:  Aidan E Gilchrist; Brendan A C Harley
Journal:  Adv Healthc Mater       Date:  2022-01-07       Impact factor: 11.092

3.  Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis.

Authors:  Bin Guo; Xinxin Huang; Man Ryul Lee; Sang A Lee; Hal E Broxmeyer
Journal:  Nat Med       Date:  2018-01-29       Impact factor: 53.440

4.  Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization.

Authors:  Wei Liu; Wei Du; Xun Shang; Lei Wang; Chris Evelyn; Maria Carolina Florian; Marnie A Ryan; Ahmad Rayes; Xueheng Zhao; Kenneth Setchell; Jarek Meller; Fukun Guo; Nicolas Nassar; Hartmut Geiger; Qishen Pang; Yi Zheng
Journal:  Leukemia       Date:  2018-09-25       Impact factor: 11.528

5.  Mesenchymal COX2-PG secretome engages NR4A-WNT signalling axis in haematopoietic progenitors to suppress anti-leukaemia immunity.

Authors:  Limei Wu; Surya Amarachintha; Jian Xu; Frank Oley; Wei Du
Journal:  Br J Haematol       Date:  2018-08-14       Impact factor: 6.998

6.  Encapsulation of murine hematopoietic stem and progenitor cells in a thiol-crosslinked maleimide-functionalized gelatin hydrogel.

Authors:  Aidan E Gilchrist; Julio F Serrano; Mai T Ngo; Zona Hrnjak; Sanha Kim; Brendan A C Harley
Journal:  Acta Biomater       Date:  2021-06-20       Impact factor: 10.633

7.  Brief Report: A Differential Transcriptomic Profile of Ex Vivo Expanded Adult Human Hematopoietic Stem Cells Empowers Them for Engraftment Better than Their Surface Phenotype.

Authors:  Nikoletta Psatha; Grigorios Georgolopoulos; Susan Phelps; Thalia Papayannopoulou
Journal:  Stem Cells Transl Med       Date:  2017-08-11       Impact factor: 6.940

8.  Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors.

Authors:  Lu Cui; Ignacio Moraga; Tristan Lerbs; Camille Van Neste; Stephan Wilmes; Naotaka Tsutsumi; Aaron Claudius Trotman-Grant; Milica Gakovic; Sarah Andrews; Jason Gotlib; Spyros Darmanis; Martin Enge; Stephen Quake; Ian S Hitchcock; Jacob Piehler; K Christopher Garcia; Gerlinde Wernig
Journal:  Proc Natl Acad Sci U S A       Date:  2021-01-12       Impact factor: 11.205

9.  Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity.

Authors:  Rajeev Gupta; Virginia Turati; Duncan Brian; Craig Thrussel; Barry Wilbourn; Gillian May; Tariq Enver
Journal:  Cell Stem Cell       Date:  2020-03-19       Impact factor: 24.633

  9 in total

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