Literature DB >> 26745913

Flattening filter free beams from TrueBeam and Versa HD units: Evaluation of the parameters for quality assurance.

Antonella Fogliata1, Jens Fleckenstein2, Frank Schneider2, Marc Pachoud3, Sarah Ghandour3, Harald Krauss4, Giacomo Reggiori1, Antonella Stravato1, Frank Lohr2, Marta Scorsetti1, Luca Cozzi1.   

Abstract

PURPOSE: Flattening filter free (FFF) beams generated by medical linear accelerators are today clinically used for stereotactical and non-stereotactical radiotherapy treatments. Such beams differ from the standard flattened beams (FF) in the high dose rate and the profile shape peaked on the beam central axis. Definition of new parameters as unflatness and slope for FFF beams has been proposed based on a renormalization factor for FFF profiles. The present study aims to assess the dosimetric differences between FFF beams generated by linear accelerators from different vendors, and to provide renormalization and parameter data of the two kinds of units.
METHODS: Dosimetric data from two Varian TrueBeam and two Elekta Versa HD linear accelerators, all with 6 and 10 MV nominal accelerating potentials, FF and FFF modes have been collected. Renormalization factors and related fit parameters according to Fogliata et al. ["Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy," Med. Phys. 39, 6455-6464 (2012)] have been evaluated for FFF beams of both units and energies. Unflatness and slope parameters from profile curves were evaluated. Dosimetric differences in terms of beam penetration and near-the-surface dose were also assessed.
RESULTS: FFF profile parameters have been updated; renormalization factors and unflatness from the Varian units are consistent with the published data. Elekta FFF beam qualities, different from the Varian generated beams, tend to express similar behaviour as the FF beam of the corresponding nominal energy. TPR20,10 for 6 and 10 MV FF and FFF TrueBeam beams are 0.665, 0.629 (6 MV) and 0.738, 0.703 (10 MV). The same figures for Versa HD units are 0.684, 0.678 (6 MV) and 0.734, 0.721 (10 MV).
CONCLUSIONS: Renormalization factor and unflatness parameters evaluated from Varian and Elekta FFF beams are provided, in particular renormalization factors table and fit parameters.

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Year:  2016        PMID: 26745913     DOI: 10.1118/1.4938060

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

1.  Efficient independent planar dose calculation for FFF IMRT QA with a bivariate Gaussian source model.

Authors:  Feifei Li; Ji-Yeon Park; Brendan Barraclough; Bo Lu; Jonathan Li; Chihray Liu; Guanghua Yan
Journal:  J Appl Clin Med Phys       Date:  2017-02-28       Impact factor: 2.102

Review 2.  The impact of technology on the changing practice of lung SBRT.

Authors:  Marianne Camille Aznar; Samantha Warren; Mischa Hoogeman; Mirjana Josipovic
Journal:  Phys Med       Date:  2018-01-10       Impact factor: 2.685

3.  Calculated relative biological effectiveness (RBE) for initial DNA double-strand breaks (DSB) from flattening filter and flattening filter-free 6 MV X-ray fields.

Authors:  Hisashi Nakano; Daisuke Kawahara; Satoshi Tanabe; Satoru Utsunomiya; Takeshi Takizawa; Madoka Sakai; Toshimichi Nakano; Atsushi Ohta; Motoki Kaidu; Hiroyuki Ishikawa
Journal:  BJR Open       Date:  2021-07-05
  3 in total

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