Literature DB >> 26743337

Genetic Diversity among Group A Streptococcus Isolated from Throats of Healthy and Symptomatic Children.

Smriti Chauhan1, Nitin Kashyap2, Anil Kanga3, Kamlesh Thakur4, Anuradha Sood4, Lata Chandel4.   

Abstract

BACKGROUND: Group A streptococcus (GAS) is the commonest bacterial cause of pharyngitis. Children in the age group of 5-15 years are most commonly affected. It can also colonize throats of healthy children in this age group. Both cases and carriers can transmit it in the community.
METHODS: Throat swab samples were collected from 1849 asymptomatic and 371 symptomatic children.
RESULTS: The rate of isolation of GAS was 1.41% among the asymptomatic group and 7.55% among the symptomatic group. Nine different emm types were encountered in the asymptomatic children and 14 among the symptomatic children.
CONCLUSION: Throat swab cultures must be used in all cases of pharyngitis. Early and appropriate antibiotic therapy will prevent complications. Asymptomatic throat carriage of GAS in children was low in our study. However, they can still act as reservoirs. Emm typing helps in understanding epidemiology and finding new types.
© The Author [2016]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  Group A streptococcus; carrier; pharyngitis

Mesh:

Substances:

Year:  2016        PMID: 26743337      PMCID: PMC4886122          DOI: 10.1093/tropej/fmv092

Source DB:  PubMed          Journal:  J Trop Pediatr        ISSN: 0142-6338            Impact factor:   1.165


  15 in total

1.  Group A streptococcal sore throat in a periurban population of northern India: a one-year prospective study.

Authors:  S Nandi; R Kumar; P Ray; H Vohra; N K Ganguly
Journal:  Bull World Health Organ       Date:  2001       Impact factor: 9.408

2.  Asymptomatic throat carriage rate and antimicrobial resistance pattern of Streptococcus pyogenes in Nepalese school children.

Authors:  S P Dumre; K Sapkota; N Adhikari; D Acharya; M Karki; S Bista; S R Basanyat; S K Joshi
Journal:  Kathmandu Univ Med J (KUMJ)       Date:  2009 Oct-Dec

3.  High diversity of group A streptococcal emm types among healthy schoolchildren in Ethiopia.

Authors:  Alemseged Abdissa; Daniel Asrat; Göran Kronvall; Belay Shittu; Dilachew Achiko; Mohammed Zeidan; Lawrence K Yamuah; Abraham Aseffa
Journal:  Clin Infect Dis       Date:  2006-04-13       Impact factor: 9.079

4.  Isolation of group A beta-hemolytic streptococci in the tonsillopharynx of school children in Madras City and correlation with their clinical features.

Authors:  S Rajkumar; R Krishnamurthy
Journal:  Jpn J Infect Dis       Date:  2001-08       Impact factor: 1.362

5.  Antibiotic resistance and genotypic characteristics of group a streptococci associated with acute pharyngitis in Korea.

Authors:  Sunjoo Kim; Nam Yong Lee
Journal:  Microb Drug Resist       Date:  2004       Impact factor: 3.431

6.  Isolation rates of Streptococcus pyogenes in patients with acute pharyngotonsillitis and among healthy school children in Iran.

Authors:  A Jasir; A Noorani; A Mirsalehian; C Schalen
Journal:  Epidemiol Infect       Date:  2000-02       Impact factor: 2.451

7.  The rate of asymptomatic throat carriage of group A Streptococcus in school children and associated ASO titers in Duzce, Turkey.

Authors:  C Elif Ozturk; Taner Yavuz; Demet Kaya; Muhterem Yucel
Journal:  Jpn J Infect Dis       Date:  2004-12       Impact factor: 1.362

8.  Typing of Streptococcus pyogenes strains isolated from throat infections in the region of Aachen, Germany.

Authors:  C M Brandt; B Spellerberg; M Honscha; N D Truong; B Hoevener; R Lütticken
Journal:  Infection       Date:  2001 May-Jun       Impact factor: 3.553

9.  Epidemiology and antibiotic resistance of group A streptococci isolated from healthy schoolchildren in Korea.

Authors:  Sunjoo Kim; Nam Yong Lee
Journal:  J Antimicrob Chemother       Date:  2004-07-21       Impact factor: 5.790

10.  Group A streptococcal infections in children.

Authors:  Andrew C Steer; Margaret H Danchin; Jonathan R Carapetis
Journal:  J Paediatr Child Health       Date:  2007-04       Impact factor: 1.954

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