Literature DB >> 26743050

[Intrinsic factors, genes, and skin aging].

E Makrantonaki1,2, G P Pfeifer3, C C Zouboulis4.   

Abstract

Skin aging is determined by a combination of endogenous and environmental influences, including epigenetic, posttranslational, microbial, and lifestyle factors. In particular genetic changes, programmed or not, play a pivotal role and understanding of these complex mechanisms may contribute to the prevention of age-related diseases and extension of healthy lifespan. In this article, new knowledge about genes and biological processes that can significantly affect skin homeostasis in old age and can lead to the typical morphological and physiological characteristics of aging skin are summarized.

Keywords:  Epigenetics; Gene expression; Genetics; Mutations; Skin homeostasis

Mesh:

Year:  2016        PMID: 26743050     DOI: 10.1007/s00105-015-3746-2

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  26 in total

Review 1.  Progeria syndromes and ageing: what is the connection?

Authors:  Christopher R Burtner; Brian K Kennedy
Journal:  Nat Rev Mol Cell Biol       Date:  2010-08       Impact factor: 94.444

2.  [Skin aging: Molecular understanding of extrinsic and intrinsic processes].

Authors:  E Makrantonaki; M Vogel; K Scharffetter-Kochanek; C C Zouboulis
Journal:  Hautarzt       Date:  2015-10       Impact factor: 0.751

Review 3.  Progeroid syndromes and UV-induced oxidative DNA damage.

Authors:  York Kamenisch; Mark Berneburg
Journal:  J Investig Dermatol Symp Proc       Date:  2009-08

4.  Neuropeptides and skin aging.

Authors:  Rana Elewa; Evgenia Makrantonaki; Christos C Zouboulis
Journal:  Horm Mol Biol Clin Investig       Date:  2013-12

5.  Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.

Authors:  Daniel M Waldera Lupa; Faiza Kalfalah; Kai Safferling; Petra Boukamp; Gereon Poschmann; Elena Volpi; Christine Götz-Rösch; Francoise Bernerd; Laura Haag; Ulrike Huebenthal; Ellen Fritsche; Fritz Boege; Niels Grabe; Julia Tigges; Kai Stühler; Jean Krutmann
Journal:  J Invest Dermatol       Date:  2015-03-27       Impact factor: 8.551

Review 6.  Clinical aspects and molecular diagnostics of skin aging.

Authors:  Christos C Zouboulis; Evgenia Makrantonaki
Journal:  Clin Dermatol       Date:  2011 Jan-Feb       Impact factor: 3.541

7.  William J. Cunliffe Scientific Awards. Characteristics and pathomechanisms of endogenously aged skin.

Authors:  Evgenia Makrantonaki; Christos C Zouboulis
Journal:  Dermatology       Date:  2007       Impact factor: 5.366

8.  Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging.

Authors:  Jenny S Breitenbach; Mark Rinnerthaler; Andrea Trost; Manuela Weber; Alfred Klausegger; Christina Gruber; Daniela Bruckner; Herbert A Reitsamer; Johann W Bauer; Michael Breitenbach
Journal:  Aging (Albany NY)       Date:  2015-06       Impact factor: 5.682

9.  Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth.

Authors:  Sylvia Koch; Omar Garcia Gonzalez; Robin Assfalg; Adrian Schelling; Patrick Schäfer; Karin Scharffetter-Kochanek; Sebastian Iben
Journal:  Cell Cycle       Date:  2014-04-29       Impact factor: 4.534

10.  DNA methylation age of human tissues and cell types.

Authors:  Steve Horvath
Journal:  Genome Biol       Date:  2013       Impact factor: 13.583

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  1 in total

1.  Detection of genomic structure variants associated with wrinkled skin in Xiang pig by next generation sequencing.

Authors:  Liu Xiaoli; Hu Fengbin; Huang Shihui; Niu Xi; Li Sheng; Wang Zhou; Ran Xueqin; Wang Jiafu
Journal:  Aging (Albany NY)       Date:  2021-11-27       Impact factor: 5.682

  1 in total

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