Literature DB >> 26740483

Coronary revascularisation in older patients with non-ST elevation acute coronary syndromes.

Hannah Sinclair1, Vijay Kunadian1.   

Abstract

With an ageing population, older patients with non-ST elevation acute coronary syndrome are at higher risk of adverse outcomes but are far less likely to receive invasive revascularisation, contemporary antiplatelet therapy or drug-eluting stents than their younger counterparts. Accurate risk stratification in the older age groups may aid individualised decision-making with respect to identifying which patients will benefit most from invasive revascularisation, but more research is needed in this field. Based on current knowledge in this field, it would be appropriate following risk stratification to offer optimal medical therapy plus invasive care to older patients at high risk of future cardiovascular events but at low risk of complications and to offer optimal medical therapy alone to those who are deemed low risk of future events with high risk of developing procedural complications and severely frail patients. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

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Year:  2016        PMID: 26740483     DOI: 10.1136/heartjnl-2015-307859

Source DB:  PubMed          Journal:  Heart        ISSN: 1355-6037            Impact factor:   5.994


  6 in total

1.  Five-year clinical outcomes in patients with frailty aged ≥75 years with non-ST elevation acute coronary syndrome undergoing invasive management.

Authors:  Hanna Ratcovich; Benjamin Beska; Greg Mills; Lene Holmvang; Jennifer Adams-Hall; Hannah Stevenson; Murugapathy Veerasamy; Chris Wilkinson; Vijay Kunadian
Journal:  Eur Heart J Open       Date:  2022-05-16

2.  The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome.

Authors:  Danny Chan; Carmen Martin-Ruiz; Gabriele Saretzki; Dermot Neely; Weiliang Qiu; Vijay Kunadian
Journal:  PLoS One       Date:  2020-01-10       Impact factor: 3.240

3.  Impact of multimorbidity on long-term outcomes in older adults with non-ST elevation acute coronary syndrome in the North East of England: a multi-centre cohort study of patients undergoing invasive care.

Authors:  Benjamin Beska; Greg B Mills; Hanna Ratcovich; Chris Wilkinson; Abdulla A Damluji; Vijay Kunadian
Journal:  BMJ Open       Date:  2022-07-26       Impact factor: 3.006

4.  Engaging older patients in cardiovascular research: observational analysis of the ICON-1 study.

Authors:  Hannah Sinclair; Jonathan A Batty; Weiliang Qiu; Vijay Kunadian
Journal:  Open Heart       Date:  2016-08-03

Review 5.  Takotsubo cardiomyopathy and acute coronary syndromes: Are they always mutually exclusive?

Authors:  Kenan Yalta; Fatih Ucar; Mustafa Yilmaztepe; Cafer Zorkun
Journal:  Indian Heart J       Date:  2017-08-14

6.  Invasive versus non-invasive management of older patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data.

Authors:  Amit Kaura; Jonathan A C Sterne; Adam Trickey; Sam Abbott; Abdulrahim Mulla; Benjamin Glampson; Vasileios Panoulas; Jim Davies; Kerrie Woods; Joe Omigie; Anoop D Shah; Keith M Channon; Jonathan N Weber; Mark R Thursz; Paul Elliott; Harry Hemingway; Bryan Williams; Folkert W Asselbergs; Michael O'Sullivan; Graham M Lord; Narbeh Melikian; Thomas Johnson; Darrel P Francis; Ajay M Shah; Divaka Perera; Rajesh Kharbanda; Riyaz S Patel; Jamil Mayet
Journal:  Lancet       Date:  2020-08-29       Impact factor: 79.321

  6 in total

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