Literature DB >> 26739751

Iron-catalyzed direct α-arylation of α-amino carbonyl compounds with indoles.

Yan Zhang1, Minjie Ni1, Bainian Feng1.   

Abstract

A mild and general α-arylation of α-amino carbonyls with indoles catalyzed by Fe(ClO4)3 has been developed. C-H activation is smoothly fulfilled by using TBHP as the oxidant with good yields. Two hydrogen dissociations make this transformation more environmentally benign because of high atom efficiency.

Entities:  

Year:  2016        PMID： 26739751     DOI： 10.1039/c5ob02325d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Photoredox Cross-Dehydrogenative Coupling of N-Aryl Glycines Mediated by Mesoporous Graphitic Carbon Nitride: An Environmentally Friendly Approach to the Synthesis of Non-Proteinogenic α-Amino Acids (NPAAs) Decorated with Indoles.

Authors:  Lorenzo Poletti; Daniele Ragno; Olga Bortolini; Francesco Presini; Fabio Pesciaioli; Stefano Carli; Stefano Caramori; Alessandra Molinari; Alessandro Massi; Graziano Di Carmine
Journal:  J Org Chem       Date:  2022-05-27       Impact factor: 4.198

2.  One-Pot Three-Component Coupling Reaction of α-Amino Aryl Ketones, Indoles, and Perbromomethane Under Mild Conditions.

Authors:  Hao Lu; Yuxuan Liu; Wei Deng; Renhua Qiu; Jiannan Xiang
Journal:  Front Chem       Date:  2022-02-04       Impact factor: 5.221

3.  Ketoxime peptide ligations: oxidative couplings of alkoxyamines to N-aryl peptides.

Authors:  Quibria A E Guthrie; Hailey A Young; Caroline Proulx
Journal:  Chem Sci       Date:  2019-08-29       Impact factor: 9.825
  3 in total

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