Literature DB >> 26737002

Design of Bioprosthetic Aortic Valves using biaxial test data.

Y Dabiri, K Paulson, J Tyberg, J Ronsky, I Ali, E Di Martino, K Narine.   

Abstract

Bioprosthetic Aortic Valves (BAVs) do not have the serious limitations of mechanical aortic valves in terms of thrombosis. However, the lifetime of BAVs is too short, often requiring repeated surgeries. The lifetime of BAVs might be improved by using computer simulations of the structural behavior of the leaflets. The goal of this study was to develop a numerical model applicable to the optimization of durability of BAVs. The constitutive equations were derived using biaxial tensile tests. Using a Fung model, stress and strain data were computed from biaxial test data. SolidWorks was used to develop the geometry of the leaflets, and ABAQUS finite element software package was used for finite element calculations. Results showed the model is consistent with experimental observations. Reaction forces computed by the model corresponded with experimental measurements when the biaxial test was simulated. As well, the location of maximum stresses corresponded to the locations of frequent tearing of BAV leaflets. Results suggest that BAV design can be optimized with respect to durability.

Entities:  

Mesh:

Year:  2015        PMID: 26737002     DOI: 10.1109/EMBC.2015.7319102

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN: 1557-170X


  1 in total

1.  Experimental Metabolic Syndrome Model Associated with Mechanical and Structural Degenerative Changes of the Aortic Valve.

Authors:  Jason L Go; Komal Prem; Mohammed A Al-Hijji; Qing Qin; Christopher Noble; Melissa D Young; Lilach O Lerman; Amir Lerman
Journal:  Sci Rep       Date:  2018-12-13       Impact factor: 4.379

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.