Literature DB >> 26734801

PROPOSAL OF A REVISIONAL SURGERY TO TREAT NON-INSULINOMA HYPERINSULINEMIC HYPOGLICEMIA POSTGASTRIC BYPASS.

José Sampaio-Neto1, Alcides José Branco-Filho1, Luis Sérgio Nassif1, André Thá Nassif1, Flávia David João De Masi1, Daniele Rezende Ximenez1.   

Abstract

BACKGROUND: Hyperinsulinemic hypoglicemia with severe neuroglycopenic symptoms has been identified as a late and rare complication in patients submitted to Roux-en-Y gastric bypass. However, the potential gravity of its manifestations requires effective treatment of this condition. The absence of treatment makes it necessary to develop more effective clinical or surgical methods. AIM: To present one surgical option to revisional surgery in the treatment of hyperinsulinemic hypoglicemia Methods : The procedure consists in reconstituting alimentary transit through the duodenum and proximal jejunum, while keeping the restrictive part of the gastric bypass. As an additional strategy to maintain weight loss, is realized gastric fundus resection, aiming to suppress ghrelin production more effectively.
RESULTS: It was used in three patients with successful results in one year of follow-up.
CONCLUSION: The procedure to reconstruct the food transit through the duodenum and proximal jejunum, keeping the restrictive component of gastric bypass in the treatment of hyperinsulinemic hypoglycemia showed good initial results and validated its application in other cases with this indication.

Entities:  

Mesh:

Year:  2015        PMID: 26734801      PMCID: PMC4755183          DOI: 10.1590/S0102-6720201500040015

Source DB:  PubMed          Journal:  Arq Bras Cir Dig        ISSN: 0102-6720


  15 in total

Review 1.  Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health.

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Journal:  Obes Res       Date:  1998-09

2.  [Insufficient loss of weight and/or absence of DM2 remission after Roux-en-Y gastric bypass: factors that may influence the unsatisfactory results].

Authors:  Anna Christina Charbel Costa; Mariana Camara Martins Bezerra Furtado; Eudes Paiva de Godoy; Elenir Rose Jardim Cury Pontes; João Ricardo Filgueiras Tognini; Maria Lúcia Ivo
Journal:  Arq Bras Cir Dig       Date:  2013-06

3.  Noninsulinoma pancreatogenous hypoglycemia syndrome: an update in 10 surgically treated patients.

Authors:  G B Thompson; F J Service; J C Andrews; R V Lloyd; N Natt; J A van Heerden; C S Grant
Journal:  Surgery       Date:  2000-12       Impact factor: 3.982

4.  Reversible hyperinsulinemic hypoglycemia after gastric bypass: a consequence of altered nutrient delivery.

Authors:  Tracey McLaughlin; Marcia Peck; Jens Holst; Carolyn Deacon
Journal:  J Clin Endocrinol Metab       Date:  2010-02-04       Impact factor: 5.958

5.  Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery.

Authors:  Geoffrey J Service; Geoffrey B Thompson; F John Service; James C Andrews; Maria L Collazo-Clavell; Ricardo V Lloyd
Journal:  N Engl J Med       Date:  2005-07-21       Impact factor: 91.245

6.  Post-prandial hypoglycemia after bariatric surgery: pharmacological treatment with verapamil and acarbose.

Authors:  Rodrigo O Moreira; Rustan B M Moreira; Nikolas A M Machado; Tatiana B Gonçalves; Walmir F Coutinho
Journal:  Obes Surg       Date:  2008-06-20       Impact factor: 4.129

7.  Short-term effect of gastric bypass in obese diabetic patients.

Authors:  Aluisio Stoll; Jean Carl Silva; Luiz Carlos Von Bahten; Giovana Gugelmin; André Berton Vedan; Bárbara Vicente de Souza
Journal:  Rev Col Bras Cir       Date:  2013 Jan-Feb

Review 8.  Metabolic surgery, weight regain and diabetes re-emergence.

Authors:  Josemberg M Campos; Daniel C Lins; Lyz B Silva; José Guido C Araujo-Junior; Jorge L M Zeve; Álvaro A B Ferraz
Journal:  Arq Bras Cir Dig       Date:  2013

9.  Insulin, C-peptide and proinsulin for the biochemical diagnosis of hypoglycaemia related to endogenous hyperinsulinism.

Authors:  D Vezzosi; A Bennet; J Fauvel; P Caron
Journal:  Eur J Endocrinol       Date:  2007-07       Impact factor: 6.664

10.  Insulinoma misdiagnosed as dumping syndrome after bariatric surgery.

Authors:  Leao Zagury; Rodrigo O Moreira; Erika P Guedes; Walmir F Coutinho; Jose C Appolinario
Journal:  Obes Surg       Date:  2004-01       Impact factor: 4.129

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