Literature DB >> 26731823

Left Ventricular Diastolic Dysfunction in Primary Hypertension and its Relation with Leisure Time Physical Activity.

Vikas Ratnaparkhe, Amit Bhangale.   

Abstract

OBJECTIVE: Left ventricular diastolic dysfunction with preserved ejection fraction is associated with an increased risk of morbidity and mortality. Population-based survey studied the associations between diastolic dysfunction in primary hypertension and its association with lifestyle--as one of risk factors. Exercise prevents and prolongs the degenerative changes but whether leisure time physical activity (LTPA) is associated with similar effects is being studied here.
METHODS: Total 301 patients of age 30-60 year old with essential hypertension were included in prospective observational study. Patients were classified according to their leisure time physical activity and subjected for echocardiography and color Doppler.
RESULTS: Out of 301 patients, 149 (49.66%) were sedentary during leisure time, out of which 114 (76.5%) were having diastolic dysfunction and 35 (23.5%) were normal, while 104 (34.66%) were having moderate physical activity in which 66 (63%) were normal. Twenty-nine (60%) of 48 vigorously active were found to be normal. By using Fisher's exact test p-value was < 0.05.
CONCLUSION: In this study, a sedentary lifestyle is found to be associated with a rapid decline of ventricular compliance. Physical activity in any form has definite protective role in prevention of degenerative changes occurring inside the body.

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Mesh:

Year:  2015        PMID: 26731823

Source DB:  PubMed          Journal:  J Assoc Physicians India        ISSN: 0004-5772


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