Literature DB >> 26731729

Correction: Investigation of Susceptibility Genes Triggering Lachrymal/Salivary Gland Lesion Complications in Japanese Patients with Type 1 Autoimmune Pancreatitis.

Takaya Oguchi, Masao Ota, Tetsuya Ito, Hideaki Hamano, Norikazu Arakura, Yoshihiko Katsuyama, Akira Meguro, Shigeyuki Kawa.   

Abstract

Entities:  

Year:  2016        PMID: 26731729      PMCID: PMC4701721          DOI: 10.1371/journal.pone.0146738

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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There are errors in the ninth, tenth and eleventh sentences of the Abstract. The correct sentences are: Individual genotyping of KLF7 rs2284932 revealed that the frequency of the minor C allele was significantly increased (P = 0.00062, Pc = 0.003, OR = 2.98, 95%CI = 1.58–5.65) in group A. The minor T allele of rs4473559 in FRMD4 demonstrated a significant association in the A group (P = 0.00015, OR = 3.38, 95%CI = 1.77–6.45). In the LOC101928923 gene, the frequency of the minor T allele of rs4379306 was significantly decreased in group A in both TaqMan and GWAS analyses. Lastly, the minor C allele of MPPED2 rs514644 carried a significantly increased risk of complications. There is an error in the third sentence of the Genetic Analysis section of the Results. The correct sentence is: The results for strong signals (P<0.0001) are shown in Table 1. There are also errors in the penultimate sentence of this section. The correct sentence is: In the LOC101928923 gene, the frequency of the minor T allele of rs4379306 was significantly decreased (P = 0.011, OR = 0.43) in both TaqMan and GWAS analyses in the A group (Table 5). There is an error in Table 3. The P value for rs2284932 should be CC+TC/TT. Please see the corrected Table 3 here.
Table 3

Association analysis of single nucleotide polymorphisms in the KLF7 gene.

dbSNP IDChrom. locationTyping methodAllelesFrequency (%)P valuePc valueOR (95% CI)
A groupB group
rs2287505207655331GWASC>AA0.0272.74(1.09–6.90)
rs1263615207667483TaqManA>GA74.068.6G0.7583.0321.10(0.61–1.96)
G26.031.4GG+GA/AA0.5672.2681.26(0.57–2.81)
rs768090207711824TaqManA>TA74.083.3T0.0910.3641.80(0.91–3.57)
T26.016.7TT+TA/AA0.0470.1882.28(1.01–5.16)
rs10195536207715065GWAST>AA0.0163.79(1.21–11.92)
rs2284932207720754TaqManT>CT90.095.1C0.000620.0032.98(1.58–5.65)
C10.04.9CC+TC/TT0.000370.0024.37(1.90–10.02)
GWASC0.00000214.35(2.32–8.16)
rs12466923207721800TaqManA>CA60.081.4C0.0390.1562.16 (1.03–4.54)
C40.018.6CC+AC/AA0.00930.0373.10(1.30–7.38)

A group: with lachrymal/salivary gland lesions, B group: without lachrymal/salivary gland lesions, dbSNP ID: SNP database identification, Chrom: chromosome, Pc: corrected P

A group: with lachrymal/salivary gland lesions, B group: without lachrymal/salivary gland lesions, dbSNP ID: SNP database identification, Chrom: chromosome, Pc: corrected P
  1 in total

1.  Investigation of susceptibility genes triggering lachrymal/salivary gland lesion complications in Japanese patients with type 1 autoimmune pancreatitis.

Authors:  Takaya Oguchi; Masao Ota; Tetsuya Ito; Hideaki Hamano; Norikazu Arakura; Yoshihiko Katsuyama; Akira Meguro; Shigeyuki Kawa
Journal:  PLoS One       Date:  2015-05-18       Impact factor: 3.240

  1 in total

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