Literature DB >> 26730093

Preventing Delayed Gastric Emptying After Whipple's Procedure-Isolated Roux Loop Reconstruction With Pancreaticogastrostomy.

Asuri Krishna1, Virinder Kumar Bansal1, Subodh Kumar1, P Sridhar1, Sameer Kapoor1, Mahesh C Misra1, Pramod Garg1.   

Abstract

Although delayed gastric emptying (DGE) after Whipple's pancreaticoduodenectomy is not life-threatening and can be treated conservatively, it results in discomfort and significant prolongation of the hospital stay and adds on to the hospital costs. To overcome this problem, we started using the isolated loop technique of reconstruction along with pancreaticogastrostomy and we present our series using this technique. All consecutive patients undergoing Whipple's pancreaticoduodenectomy in a single surgical unit from January 2009 until December 2012 were included. In the absence of hepatic and peritoneal metastasis, resection (Whipple's procedure) with curative intent was done using isolated loop technique with pancreaticogastrostomy. Delayed gastric emptying was assessed clinically and on oral gastrograffin study. Bile reflux was also assessed on clinical parameters and evidence of beefy friable gastric mucosa on upper GI endoscopy and presence of reflux on hepatobiliary scintigraphy. A total of 52 patients were operated using this technique from January 2009 to October 2012. The mean operative time was 260.8 ± 50.3, and the mean operative blood loss was 1,068.0 ± 606.1 ml. Mean gastric emptying time 106.0 ± 6.1 min (89-258 min). Three out of the 52(5.7 %) patients had persistent vomiting in the post-operative period requiring reinsertion of NG tube. A HIDA scan done on POD7 for all patients did not show any evidence of bile reflux in any of the patients. Pancreatogastrostomy with isolated loop in pancreaticoduodenal resection markedly reduces the post-operative incidence of alkaline reflux gastritis and DGE.

Entities:  

Keywords:  Bile reflux; Delayed gastric emptying; Isolated loop; Whipple's procedure

Year:  2013        PMID: 26730093      PMCID: PMC4692950          DOI: 10.1007/s12262-013-0992-3

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  19 in total

1.  Factors influencing delayed gastric emptying after pylorus-preserving pancreatoduodenectomy.

Authors:  Yoon-Chan Park; Sun-Whe Kim; Jin-Young Jang; Young Joon Ahn; Yong-Hyun Park
Journal:  J Am Coll Surg       Date:  2003-06       Impact factor: 6.113

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Journal:  Ann Surg       Date:  2005-12       Impact factor: 12.969

4.  Different gastric emptying of solid and liquid meals after pylorus-preserving pancreatoduodenectomy.

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Journal:  Br J Surg       Date:  1998-07       Impact factor: 6.939

5.  Delayed gastric emptying after pancreaticoduodenectomy and pancreaticogastrostomy.

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Journal:  Eur J Surg       Date:  1999-06

6.  Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy.

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Journal:  Arch Surg       Date:  2003-12

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Journal:  J Surg Res       Date:  1987-05       Impact factor: 2.192

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Journal:  Am J Surg       Date:  1996-07       Impact factor: 2.565

Review 9.  The challenge of pancreatic anastomosis.

Authors:  Axel Kleespies; Markus Albertsmeier; Firas Obeidat; Hendrik Seeliger; Karl-Walter Jauch; Christiane J Bruns
Journal:  Langenbecks Arch Surg       Date:  2008-04-01       Impact factor: 3.445

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Journal:  Arch Surg       Date:  1995-08
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  2 in total

Review 1.  Delayed Gastric Emptying and Gastric Remnant Function After Pancreaticoduodenectomy: A Systematic Review of Objective Assessment Modalities.

Authors:  Tim H-H Wang; Anthony Y Lin; Keno Mentor; Gregory O'Grady; Sanjay Pandanaboyana
Journal:  World J Surg       Date:  2022-10-23       Impact factor: 3.282

2.  Protein-energy malnutrition worsens hospitalization outcomes of patients with pancreatic cancer undergoing open pancreaticoduodenectomy.

Authors:  Yu-Xiu Zhang; Yi-Feng Yang; Pu Han; Peng-Cheng Ye; Hao Kong
Journal:  Updates Surg       Date:  2022-05-07
  2 in total

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