Literature DB >> 26728612

A prospective cohort study of the clinical presentation of non-traumatic osteonecrosis of the femoral head: spine and knee symptoms as clinical presentation of hip osteonecrosis.

Jean-Philippe Hauzeur1, Michel Malaise2, Viviane de Maertelaer3.   

Abstract

PURPOSE: To study the clinical presentation of femoral head osteonecrosis (ONFH). Publications dedicated to this aspect of ONFH are rare. Our aim was to systematically collect and describe the clinical data.
METHODS: A prospective survey was conducted in a cohort of ONFH recruited from a dedicated clinic for osteonecrosis. The history of symptoms, medical management, and physical findings were obtained from 88 patients suffering from 125 ONFH. Subgroups were formed: bilateral versus unilateral ONFH, radiological stages 1-2 (pre-fractured) versus fractured stage 3 versus stage 4.
RESULTS: ONFH was bilateral in 63 %, especially in corticosteroid users and in sickle-cell cases. These patients were younger but had similar BMIs compared to the unilateral cases. The pain was mechanical in 79 % of hips and inflammatory in 21 %. Acute pain at the onset was present in 55 % of hips. The localization of this pain was variable, including in the groin, the buttocks, or diffused in the lower limbs. A limp was present in 50 % of the patients, only when one hip was painful. The physical examination of the hip was normal in 31 %, especially in stages 1-2 (55 %). The diagnosis delay was 12 months, with inadequate medical management in 51 % of patients.
CONCLUSIONS: In ONFH cases, no typical clinical pattern was found. The clinical presentation was very variable, sometimes having spine or knee symptoms with a normal physical examination of the hip. ONFH should be systematically suspected in cases of onset of pain in the pelvis, buttocks, groin, and lower limbs.

Entities:  

Keywords:  Clinical feature; Diagnosis; Femoral head; Hip; Osteonecrosis; Symptoms

Mesh:

Year:  2016        PMID: 26728612     DOI: 10.1007/s00264-015-3079-x

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


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  9 in total
  11 in total

1.  Cementless total hip arthroplasty for osteonecrosis and osteoarthritis produce similar results at ten years follow-up when matched for age and gender.

Authors:  Yusuke Osawa; Taisuke Seki; Yasuhiko Takegami; Taiki Kusano; Kazuya Makida; Naoki Ishiguro
Journal:  Int Orthop       Date:  2018-05-24       Impact factor: 3.075

2.  Do femoral head collapse and the contralateral condition affect patient-reported quality of life and referral pain in patients with osteonecrosis of the femoral head?

Authors:  Yusuke Osawa; Taisuke Seki; Yasuhiko Takegami; Takehiro Kasai; Yoshitoshi Higuchi; Naoki Ishiguro
Journal:  Int Orthop       Date:  2018-03-09       Impact factor: 3.075

3.  Hip function in patients undergoing conservative treatment for osteonecrosis of the femoral head.

Authors:  Yusuke Osawa; Yasuhiko Takegami; Daisaku Kato; Masanori Okamoto; Hiroki Iida; Shiro Imagama
Journal:  Int Orthop       Date:  2022-09-14       Impact factor: 3.479

4.  Osteonecrosis in sickle cell disease patients from Bahia, Brazil: a cross-sectional study.

Authors:  Gildasio Daltro; Bruno Adelmo Franco; Thiago Batista Faleiro; Davi Araujo Veiga Rosário; Paula Braga Daltro; Vitor Fortuna
Journal:  Int Orthop       Date:  2018-03-26       Impact factor: 3.075

5.  Inefficacy of autologous bone marrow concentrate in stage three osteonecrosis: a randomized controlled double-blind trial.

Authors:  Jean-Philippe Hauzeur; Viviane De Maertelaer; Etienne Baudoux; Michel Malaise; Yves Beguin; Valérie Gangji
Journal:  Int Orthop       Date:  2017-10-07       Impact factor: 3.075

6.  Bioinformatics analysis and identification of genes and molecular pathways in steroid-induced osteonecrosis of the femoral head.

Authors:  Tianye Lin; Weijian Chen; Peng Yang; Ziqi Li; Qiushi Wei; Du Liang; Haibin Wang; Wei He; Qingwen Zhang
Journal:  J Orthop Surg Res       Date:  2021-05-20       Impact factor: 2.359

Review 7.  Corticosteroid-induced Osteonecrosis of the Femoral Head: Detection, Diagnosis, and Treatment in Earlier Stages.

Authors:  Li-Hua Liu; Qing-Yu Zhang; Wei Sun; Zi-Rong Li; Fu-Qiang Gao
Journal:  Chin Med J (Engl)       Date:  2017-11-05       Impact factor: 2.628

8.  Identification of potential autophagy-related genes in steroid-induced osteonecrosis of the femoral head via bioinformatics analysis and experimental verification.

Authors:  Xue-Zhen Liang; Di Luo; Yan-Rong Chen; Jia-Cheng Li; Bo-Zhao Yan; Yan-Bo Guo; Ming-Tao Wen; Bo Xu; Gang Li
Journal:  J Orthop Surg Res       Date:  2022-02-12       Impact factor: 2.359

Review 9.  The disappearance of femoral head and neck resulting from extensive bone defect caused by secondary syphilis: a case report and literature review.

Authors:  Xiao Liang; Tang Liu; Chuang Yuan; Wanchun Wang; Peixiong Liang
Journal:  BMC Musculoskelet Disord       Date:  2018-07-25       Impact factor: 2.362

10.  MiR-596 inhibits osteoblastic differentiation and cell proliferation by targeting Smad3 in steroid-induced osteonecrosis of femoral head.

Authors:  Ligong Fu; Huawei Liu; Weijun Lei
Journal:  J Orthop Surg Res       Date:  2020-05-14       Impact factor: 2.359

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