| Literature DB >> 26728527 |
Abstract
The bone has the functions of mineral reservoir and mechanical support as skeleton. Bone remodeling is the adult mode of bone metabolism, replacing old bone tissue to new one. Bone strength is determined by bone volume, structure and quality such as micro damage, degree of mineralization and collagen cross linkage, which are all controlled by bone remodeling. Bone strength decreases under high turn-over condition by decreasing bone volume and deterioration of bone structure, which also decreases under low turn-over condition by increased micro damage, increasing mineralization and AGE collagen cross linkage.Mesh:
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Year: 2016 PMID: 26728527 DOI: CliCa16011727
Source DB: PubMed Journal: Clin Calcium ISSN: 0917-5857