| Literature DB >> 26727257 |
Mario Waespy, Thaddeus T Gbem, Leroy Elenschneider, André-Philippe Jeck, Christopher J Day, Lauren Hartley-Tassell, Nicolai Bovin, Joe Tiralongo, Thomas Haselhorst, Sørge Kelm.
Abstract
Entities:
Year: 2015 PMID: 26727257 PMCID: PMC4699837 DOI: 10.1371/journal.pntd.0004344
Source DB: PubMed Journal: PLoS Negl Trop Dis ISSN: 1935-2727
Fig 2Summary of TconTS-LDs binding to glycans as determined by glycan array analysis.
TconTS-LDs binding to the glycan arrays was determined as described under Methods. Black bars indicate glycans bound by the TconTS-LDs. The presence and absence of the α-helix in TconTS-LD constructs is indicated with “+” and “-“, respectively. Further binding data (S2 Fig) and all glycans on the arrays (S1 Table) are available as Supporting Information.
Fig 7Contact site between TconTS-CD and LD.
Homology model of TconTS1 was calculated using the crystal structure of TcTS (PDB: 3b69) as template and the software Yasara. Molecular surface of TconTS1 was calculated using the surface module of Yasara Structure. Illustrated are the parts of TconTS-CD (yellow) and LD (orange), which are in close contact to each other. The α-helix connecting both domains is shown in blue.