| Literature DB >> 26726748 |
Zhong-Liu Zhou1, Wen-Qing Yin, Ya-Mei Yang, Chun-Hong He, Xiao-Na Li, Cui-Ping Zhou, Hong Guo.
Abstract
Based on bioactive screening results, two new iridoid glycosides, named rotunduside G (1) and rotunduside H (2), were isolated from the rhizomes of Cyperus rotundus, together with four known ones, negundoside (3), nishindaside (4), isooleuropein (5) and neonuezhenide (6). Their structures were elucidated on the basis of spectroscopic methods and from literature values. In mice models of despair, 1 and 2 showed significant antidepressant activity.Entities:
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Year: 2016 PMID： 26726748 DOI： 10.1248/cpb.c15-00686
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645