Literature DB >> 26726720

The Best Anticoagulation Therapy in Multiple-Trauma Patients with Mechanical Heart Valves: Evaluation of Latest Guidelines and Studies.

Aliasghar Moeinipour1, Ahmadreza Zarifian2, Mohammad Sobhan Sheikh Andalibi2, Alireza Sepehri Shamloo2, Ali Ahmadabadi2, Ahmad Amouzeshi3, Hamid Hoseinikhah1.   

Abstract

BACKGROUND: It is common practice for patients with prosthetic cardiac devices, especially heart valve prosthesis, arterial stents, defibrillators, and pacemaker devices, to use anticoagulation treatment. When these patients suffer from multiple trauma after motor vehicle accidents, the best medical management for this challenging position is mandatory. This strategy should include a rapid diagnosis of all possible multiple organ injuries, with special attention to anticoagulation therapy so as to minimize the risk of thromboembolism complication in prosthetic devices. In this review, we describe the best medical management for patients with multiple trauma who use anticoagulants after heart valve replacement.
METHODS: We searched electronic databases PubMed/Medline, Scopus, Embase, and Google Scholar using the following terms: anticoagulant, warfarin, heparin, and multiple trauma. Also, similar studies suggested by the databases were included. Non-English articles were excluded from the review.
RESULTS: For patients who use anticoagulation therapy, teamwork between cardiac surgeons, general surgeons, anesthesiologists, and cardiologists is essential. For optimal medical management, multiple consults between members of this team is mandatory for rapid diagnosis of all possible damaged organs, with special attention to the central nervous system, chest, and abdominal traumas. With this strategy, it is important to take note of anticoagulation drugs to minimize the risk of thromboembolism complications in cardiac devices.
CONCLUSION: The best anticoagulant agents for emergency operations in patients with multiple trauma who are using an anticoagulant after heart valve replacement are fresh frozen plasma (FFP) and prothrombin complex concentrates (PCC).

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Year:  2015        PMID: 26726720     DOI: 10.1532/hsf.1348

Source DB:  PubMed          Journal:  Heart Surg Forum        ISSN: 1098-3511            Impact factor:   0.676


  3 in total

1.  Anticoagulation therapy in animal research.

Authors:  Victoria Hampshire
Journal:  Lab Anim (NY)       Date:  2016-10-20       Impact factor: 12.625

2.  Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model.

Authors:  Zhong-Hua Fu; Guang-Hua Guo; Zhen-Fang Xiong; Xincheng Liao; Ming-Zhuo Liu; Jinhua Luo
Journal:  Mol Med Rep       Date:  2017-09-20       Impact factor: 2.952

3.  The Efficacy of Glasgow Coma Scale (GCS) Score and Acute Physiology and Chronic Health Evaluation (APACHE) II for Predicting Hospital Mortality of ICU Patients with Acute Traumatic Brain Injury.

Authors:  Amir Nik; Mohammad Sobhan Sheikh Andalibi; Mohammad Reza Ehsaei; Ahmadreza Zarifian; Ehsan Ghayoor Karimiani; Gholamreza Bahadoorkhan
Journal:  Bull Emerg Trauma       Date:  2018-04
  3 in total

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