Literature DB >> 26725983

Tuning the properties of a novel short cell-penetrating peptide by intramolecular cyclization with a triazole bridge.

M Horn1, F Reichart1, S Natividad-Tietz1, D Diaz2, I Neundorf1.   

Abstract

Cell-penetrating peptides (CPPs) present a versatile alternative to viral gene delivery vectors, addressing the still challenging task to suitably transport the desired gene to the target cell. In this work, the rational design of triazole-bridged CPPs and their detailed investigation concerning peptide/lipid interactions, using also NMR-based structure calculations, are reported.

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Year:  2016        PMID： 26725983     DOI： 10.1039/c5cc08938g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Cyclic Cell-Penetrating Peptides with Single Hydrophobic Groups.

Authors:  Jian Song; Ziqing Qian; Ashweta Sahni; Kuangyu Chen; Dehua Pei
Journal:  Chembiochem       Date:  2019-07-24       Impact factor: 3.164

2.  Development of a Cell-Permeable Cyclic Peptidyl Inhibitor against the Keap1-Nrf2 Interaction.

Authors:  Heba Salim; Jian Song; Ashweta Sahni; Dehua Pei
Journal:  J Org Chem       Date:  2019-10-28       Impact factor: 4.354

3.  Understanding Cell Penetration of Cyclic Peptides.

Authors:  Patrick G Dougherty; Ashweta Sahni; Dehua Pei
Journal:  Chem Rev       Date:  2019-05-14       Impact factor: 60.622

Review 4.  Genetic and Covalent Protein Modification Strategies to Facilitate Intracellular Delivery.

Authors:  Justin M Horn; Allie C Obermeyer
Journal:  Biomacromolecules       Date:  2021-12-02       Impact factor: 6.978

5.  Discovery of a Cyclic Cell-Penetrating Peptide with Improved Endosomal Escape and Cytosolic Delivery Efficiency.

Authors:  Marina Buyanova; Ashweta Sahni; Rui Yang; Amar Sarkar; Heba Salim; Dehua Pei
Journal:  Mol Pharm       Date:  2022-04-11       Impact factor: 5.364

Review 6.  Intracellular Delivery of Proteins with Cell-Penetrating Peptides for Therapeutic Uses in Human Disease.

Authors:  Ana Dinca; Wei-Ming Chien; Michael T Chin
Journal:  Int J Mol Sci       Date:  2016-02-22       Impact factor: 5.923

Review 7.  Tumor-targeting delivery of herb-based drugs with cell-penetrating/tumor-targeting peptide-modified nanocarriers.

Authors:  Dereje Kebebe; Yuanyuan Liu; Yumei Wu; Maikhone Vilakhamxay; Zhidong Liu; Jiawei Li
Journal:  Int J Nanomedicine       Date:  2018-03-09

8.  Design and biological characterization of novel cell-penetrating peptides preferentially targeting cell nuclei and subnuclear regions.

Authors:  Anja Gronewold; Mareike Horn; Ines Neundorf
Journal:  Beilstein J Org Chem       Date:  2018-06-07       Impact factor: 2.883

9.  A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery.

Authors:  Katrin Hoffmann; Nadia Milech; Suzy M Juraja; Paula T Cunningham; Shane R Stone; Richard W Francis; Mark Anastasas; Clinton M Hall; Tatjana Heinrich; Heique M Bogdawa; Scott Winslow; Marie N Scobie; Robert E Dewhurst; Laura Florez; Ferrer Ong; Maria Kerfoot; Danie Champain; Abbie M Adams; Susan Fletcher; Helena M Viola; Livia C Hool; Theresa Connor; Brooke A C Longville; Yew-Foon Tan; Karen Kroeger; Volker Morath; Gregory A Weiss; Arne Skerra; Richard M Hopkins; Paul M Watt
Journal:  Sci Rep       Date:  2018-08-22       Impact factor: 4.379

10.  Design of a novel cell-permeable chimeric peptide to promote wound healing.

Authors:  Mareike Horn; Ines Neundorf
Journal:  Sci Rep       Date:  2018-11-02       Impact factor: 4.379
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