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Literature DB >> 26725483

All-in-One azides: empowered click reaction for in vivo labeling and imaging of biomolecules.

Yaning Su¹, Li Li², Haibin Wang³, Xiaochen Wang³, Zhiyuan Zhang⁴.

Abstract

We designed and synthesized All-in-One (AIO) reactive azide reagents for bioorthogonal reactions with highly efficient Cu(I) ligand moieties, an azido group, and functional tags for imaging or purification. The AIO reagents displayed fast and efficient click ligation and can be applied in a wide range of in vivo systems.

Entities: Chemical

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Year: 2016 PMID： 26725483 DOI： 10.1039/c5cc08466k

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

7 in total

1. Bioorthogonal chemistry.

Authors: Samuel L Scinto; Didier A Bilodeau; Robert Hincapie; Wankyu Lee; Sean S Nguyen; Minghao Xu; Christopher W Am Ende; M G Finn; Kathrin Lang; Qing Lin; John Paul Pezacki; Jennifer A Prescher; Marc S Robillard; Joseph M Fox
Journal: Nat Rev Methods Primers Date: 2021-04-15

2. Discrete Cu(i) complexes for azide-alkyne annulations of small molecules inside mammalian cells.

Authors: Joan Miguel-Ávila; María Tomás-Gamasa; Andrea Olmos; Pedro J Pérez; José L Mascareñas
Journal: Chem Sci Date: 2018-01-15 Impact factor: 9.825

Review 3. Development and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal Reaction.

Authors: Li Li; Zhiyuan Zhang
Journal: Molecules Date: 2016-10-24 Impact factor: 4.411

All-in-One azides: empowered click reaction for in vivo labeling and imaging of biomolecules.

1. Bioorthogonal chemistry.

2. Discrete Cu(i) complexes for azide-alkyne annulations of small molecules inside mammalian cells.

Review 3. Development and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal Reaction.

4. Synthesis and Fluorescent Properties of Aminopyridines and the Application in "Click and Probing".

5. A palette of background-free tame fluorescent probes for intracellular multi-color labelling in live cells.

Review 6. Aryl transition metal chemical warheads for protein bioconjugation.

7. Intracellular Ruthenium-Promoted (2+2+2) Cycloadditions.