| Literature DB >> 26725232 |
D S Kalinina1, E V Frolova1, V V Lavrentyeva1, N M Dubrovskaya1,2, N Ya Lukomskaya1, K Kh Kim1, A V Zaitsev3, I A Zhuravin1,2, L G Magazanik4,5.
Abstract
We studied the delayed effects of prenatal exposure to hypoxia on the susceptibility of rats to seizures. The later was estimated using graded electroshock. The experiments were performed in two groups of 1.5-year-old male Wistar rats. The experimental group consisted of the animals that were exposed to hypoxia on day 14 of prenatal development, and the control group consisted of the animals that developed under the normal conditions. In the rats subjected to prenatal hypoxia, seizure episodes induced by weak currents in the range of 10-40 mA and their average duration were more pronounced as compared to the control animals.Entities:
Mesh：
Year: 2016 PMID： 26725232 DOI： 10.1134/S0012496615060071
Source DB: PubMed Journal: Dokl Biol Sci ISSN： 0012-4966