Literature DB >> 26724832

Anatomical and histological study to determine the border of sole skin.

Noriko Uemura1, Mutsumi Okazaki2, Hiroki Mori2.   

Abstract

PURPOSE: Transfer of a free skin graft from the submalleolar or plantar instep area to the palmoplantar area and finger defects is widely performed; however, the sites and the border of plantar skin have yet to be examined in detail. The aim of this study was to determine the border of sole skin.
METHODS: Twelve paraformaldehyde-fixed cadavers were examined. Skin specimens were harvested from an area from the top of the medial malleolus extending to the top of the lateral malleolus of the right foot. The paraffin-embedded skin specimens were analyzed using histological (hematoxylin and eosin, Fontana-Masson, and elastica van Gieson stains) and immunohistochemical (cytokeratin 9) techniques.
RESULTS: CK9-positive cells were present at the points between 21 and 78 % of the intermalleolar distance measured from the tops of the medial and lateral malleoli. The melanin index abruptly changed at the points 25 ± 7.1 and 75 ± 4.2 %. The skin thickness and amount of elastic fibers changed greatly at the points between 20 and 30 % and between 70 and 80 % of the intermalleolar distance.
CONCLUSIONS: Submalleolar skin is quite different from sole skin. The border of sole skin lies at the points between 20 and 25 % of the intermalleolar distance from the medial malleolus, which macroscopically corresponds to the border of skin maceration. It would be better to use the submalleolar area for grafts for the dorsum of the fingers or toes, and the plantar instep area for the ventral areas of the fingers or toes.

Entities:  

Keywords:  Cytokeratin 9; Palmoplantar skin; Plantar area; Skin graft; Submalleolar

Mesh:

Substances:

Year:  2016        PMID: 26724832     DOI: 10.1007/s00276-015-1609-2

Source DB:  PubMed          Journal:  Surg Radiol Anat        ISSN: 0930-1038            Impact factor:   1.246


  14 in total

1.  Regulation of keratin 9 in nonpalmoplantar keratinocytes by palmoplantar fibroblasts through epithelial-mesenchymal interactions.

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2.  WHY IS THE PALM AND SOLE SKIN WHITE?

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Authors:  J P WEBSTER
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Authors:  Timm O Engelhardt; Gabriel Djedovic; Ulrich M Rieger; Gerhard Pierer; Anton H Schwabegger
Journal:  Ann Plast Surg       Date:  2011-12       Impact factor: 1.539

5.  Effects of tretinoin on photodamaged skin. A histologic study.

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Journal:  Arch Dermatol       Date:  1991-05

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Authors:  J K Kimani
Journal:  Acta Morphol Neerl Scand       Date:  1984-12

7.  Reconstruction for palmar skin defects of the digits and hand using plantar dermal grafting.

Authors:  H Y Tanabe; A Aoyagi; Y Tai; K Kiyokawa; Y Inoue
Journal:  Plast Reconstr Surg       Date:  1998-04       Impact factor: 4.730

8.  A retrospective study of thick split-thickness plantar skin grafts to resurface the palm.

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Journal:  Ann Plast Surg       Date:  1984-06       Impact factor: 1.539

9.  Distribution of a special subset of keratinocytes characterized by the expression of cytokeratin 9 in adult and fetal human epidermis of various body sites.

Authors:  I Moll; H Heid; W W Franke; R Moll
Journal:  Differentiation       Date:  1987       Impact factor: 3.880

10.  Cytokeratin No. 9, an epidermal type I keratin characteristic of a special program of keratinocyte differentiation displaying body site specificity.

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Journal:  J Cell Biol       Date:  1986-08       Impact factor: 10.539

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  1 in total

Review 1.  Reference values for skin microanatomy: A systematic review and meta-analysis of ex vivo studies.

Authors:  Haoming Xu; Maira Fonseca; Zachary Wolner; Esther Chung; Xinyuan Wu; Shamir Geller; Stephen W Dusza; Antonio P DeRosa; Ashfaq A Marghoob; Klaus J Busam; Allan C Halpern; Michael A Marchetti
Journal:  J Am Acad Dermatol       Date:  2017-07-14       Impact factor: 11.527

  1 in total

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