| Literature DB >> 26724709 |
Abstract
The distribution of cholesterol between the two leaves of the plasma membrane in mammalian cells presents a conundrum; given cholesterol's known affinity for sphingomyelin, which resides predominantly in the exoplasmic leaf, why is it that experiment finds a majority of the cholesterol in the cytoplasmic leaf? This article reviews a recently proposed solution to this puzzle.Entities:
Keywords: Bending energy; Cholesterol; Phosphatidylethanolamine; Spontaneous curvature
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Year: 2015 PMID： 26724709 DOI： 10.1016/j.chemphyslip.2015.12.002
Source DB: PubMed Journal: Chem Phys Lipids ISSN： 0009-3084 Impact factor: 3.329