Andrew D McQuiston1, Giuseppe Muscogiuri2, U Joseph Schoepf3, Felix G Meinel4, Christian Canstein5, Akos Varga-Szemes1, Paola M Cannao'6, Julian L Wichmann7, Thomas Allmendinger8, Rozemarijn Vliegenthart9, Carlo N De Cecco2. 1. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA. 2. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA; Department of Radiological Sciences, Oncology and Pathology, University of Rome "Sapienza"-Polo Pontino, Latina, Italy. 3. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA; Department of Medicine, Division of Cardiology, Medical University of South Carolina, Charleston, SC, USA. Electronic address: schoepf@musc.edu. 4. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA; Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany. 5. Siemens Medical Solutions, Malvern, PA, USA. 6. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA; Scuola di Specializzazione in Radiodiagnostica, University of Milan, Milan, Italy. 7. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA; Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany. 8. Siemens Healthcare, Forchheim, Germany. 9. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA; Center for Medical Imaging-North East Netherlands, Department of Radiology, University Medical Center Groningen, Groningen, The Netherlands.
Abstract
OBJECTIVES: To investigate to what extent 3rd generation dual-source computed tomography (DSCT) can reduce radiation dose in coronary artery calcium scoring. METHODS: Image acquisition was performed using a stationary calcification phantom. Prospectively electrocardiogram (ECG)-triggered 120 kV sequential, and 120 and Sn100 kV ultra-high pitch (UHP) acquisitions were performed with different tube currents (80, 60, 40, 20 mA). Images were reconstructed using filtered back projection (FBP) and 3rd generation iterative reconstruction (IR). Contrast-to-noise ratio (CNR), Agatston score, calcium volume, and radiation dose were assessed. For statistical analysis Friedman tests and Wilcoxon rank sum tests were used. RESULTS: Even at reduced tube currents, the three acquisition techniques did not show significant differences in Agatston score (p=0.4) or calcium volume (p=0.08) with FBP reconstruction. Calcium volumes were significantly lower for 3rd generation IR compared to FBP reconstructions (p<0.01). CTDIvol for the 120 kV sequential, 120 and Sn100 kV UHP acquisitions at 80 and 20 mA were 1.2-0.37, 0.48-0.17, and 0.07-0.02 mGy, respectively. CONCLUSION: 3rd generation DSCT enabled a reduction of tube current in both the sequential and UHP acquisitions without significantly affecting coronary calcium scoring. Tin filtered 100 kV scanning may allow accurate quantification of calcium score without correction of the HU threshold.
OBJECTIVES: To investigate to what extent 3rd generation dual-source computed tomography (DSCT) can reduce radiation dose in coronary artery calcium scoring. METHODS: Image acquisition was performed using a stationary calcification phantom. Prospectively electrocardiogram (ECG)-triggered 120 kV sequential, and 120 and Sn100 kV ultra-high pitch (UHP) acquisitions were performed with different tube currents (80, 60, 40, 20 mA). Images were reconstructed using filtered back projection (FBP) and 3rd generation iterative reconstruction (IR). Contrast-to-noise ratio (CNR), Agatston score, calcium volume, and radiation dose were assessed. For statistical analysis Friedman tests and Wilcoxon rank sum tests were used. RESULTS: Even at reduced tube currents, the three acquisition techniques did not show significant differences in Agatston score (p=0.4) or calcium volume (p=0.08) with FBP reconstruction. Calcium volumes were significantly lower for 3rd generation IR compared to FBP reconstructions (p<0.01). CTDIvol for the 120 kV sequential, 120 and Sn100 kV UHP acquisitions at 80 and 20 mA were 1.2-0.37, 0.48-0.17, and 0.07-0.02 mGy, respectively. CONCLUSION: 3rd generation DSCT enabled a reduction of tube current in both the sequential and UHP acquisitions without significantly affecting coronary calcium scoring. Tin filtered 100 kV scanning may allow accurate quantification of calcium score without correction of the HU threshold.
Authors: Georg Apfaltrer; Moritz H Albrecht; U Joseph Schoepf; Taylor M Duguay; Carlo N De Cecco; John W Nance; Domenico De Santis; Paul Apfaltrer; Marwen H Eid; Chelsea D Eason; Zachary M Thompson; Maximilian J Bauer; Akos Varga-Szemes; Brian E Jacobs; Erich Sorantin; Christian Tesche Journal: Eur Radiol Date: 2018-02-05 Impact factor: 5.315
Authors: David Steybe; Philipp Poxleitner; Pit Jacob Voss; Marc Christian Metzger; Rainer Schmelzeisen; Fabian Bamberg; Suam Kim; Maximilian Frederik Russe Journal: BMC Med Imaging Date: 2021-10-27 Impact factor: 1.930
Authors: Marleen Vonder; Gert Jan Pelgrim; Sèvrin E M Huijsse; Mathias Meyer; Marcel J W Greuter; Thomas Henzler; Thomas G Flohr; Matthijs Oudkerk; Rozemarijn Vliegenthart Journal: Eur Radiol Date: 2016-08-29 Impact factor: 5.315