| Literature DB >> 26722587 |
Yu Pan1, Yongguang Tao2, Chunyan Fu1, Jiantao Jia3, Shuang Liu4, Desheng Xiao1.
Abstract
Myeloid sarcoma is a rare solid tumor consisting of leukemic myeloblasts and/or myeloid precursors occurring outside the blood or bone marrow. The unique site with myeloid sarcoma has been reported, the multiple sites of myeloid sarcoma have rarely been cited in the medical literature. Here we report that the unusual clinical presentation and management of myeloid sarcoma in multiple sites with PET-CT, highlighting the utility of PET-CT was useful in detecting and monitoring myeloid sarcoma. We also found that loss of TET2 and gain of 5 hmC in the case of myeloid sarcoma, indicating the mechanism for myeloid sarcoma is totally different with other hematopoietic malignancies.Entities:
Keywords: 5 hmC; CD117; MPO; Myeloid sarcoma; PET-CT; TET2
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Year: 2015 PMID： 26722587 PMCID： PMC4680532
Source DB: PubMed Journal: Int J Clin Exp Pathol ISSN： 1936-2625