Literature DB >> 26722165

Choriocarcinoma presenting with thyrotoxicosis.

David Sotello1, Ana Marcella Rivas1, Victor J Test1, Joaquin Lado-Abeal1.   

Abstract

We describe a 26-year-old man with metastatic choriocarcinoma who presented with hyperthyroidism associated with elevated β-human chorionic gonadotropin (B-HCG) and respiratory failure secondary to diffuse lung metastasis. After the first cycle of chemotherapy, the concentration of B-HCG dramatically decreased and the patient became euthyroid, allowing us to discontinue antithyroid medications. The patient's hyperthyroidism was caused by stimulation of the thyroid gland by high B-HCG levels, as shown by the marked improvement of the patient's thyroid function panel after chemotherapy.

Entities:  

Year:  2016        PMID： 26722165      PMCID： PMC4677850          DOI： 10.1080/08998280.2016.11929353

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN： 0899-8280


  6 in total

1.  Testicular choriocarcinoma presenting as hyperthyroidism.

Authors:  Pallavi Heda; Gary Cushing
Journal:  Am J Med       Date:  2013-11       Impact factor: 4.965

2.  Hyperthyroidism due to secretion of human chorionic gonadotropin in a patient with metastatic choriocarcinoma.

Authors:  Ludimyla H F Meister; Patrícia R Hauck; Hans Graf; Gisah A Carvalho
Journal:  Arq Bras Endocrinol Metabol       Date:  2005-09-12

3.  Choriogonadotropin-mediated thyrotoxicosis in a man.

Authors:  H J Cain; P R Pannall; D Kotasek; R J Norman
Journal:  Clin Chem       Date:  1991-06       Impact factor: 8.327

4.  Prevalence of paraneoplastic hyperthyroidism in patients with metastatic non-seminomatous germ-cell tumors.

Authors:  S F Oosting; E C de Haas; T P Links; D de Bruin; W J Sluiter; I J de Jong; H J Hoekstra; D T Sleijfer; J A Gietema
Journal:  Ann Oncol       Date:  2009-07-15       Impact factor: 32.976

5.  Serum human chorionic gonadotropin concentrations greater than 400,000 IU/L are invariably associated with suppressed serum thyrotropin concentrations.

Authors:  Christina M Lockwood; David G Grenache; Ann M Gronowski
Journal:  Thyroid       Date:  2009-08       Impact factor: 6.568

Review 6.  Physiological and pathological aspects of the effect of human chorionic gonadotropin on the thyroid.

Authors:  Jerome M Hershman
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2004-06       Impact factor: 4.690
  6 in total
  3 in total

1.  Severe thyrotoxicosis as initial presentation of gastric choriocarcinoma: a case report.

Authors:  Nicole M Iñiguez-Ariza; Dalia Cuenca; Juvenal Franco-Granillo; Alberto Villalobos-Prieto; Janet Pineda-Díaz; Javier Baquera-Heredia
Journal:  J Med Case Rep       Date:  2022-04-21

Review 2.  Thyroid Allostasis-Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress, and Developmental Programming.

Authors:  Apostolos Chatzitomaris; Rudolf Hoermann; John E Midgley; Steffen Hering; Aline Urban; Barbara Dietrich; Assjana Abood; Harald H Klein; Johannes W Dietrich
Journal:  Front Endocrinol (Lausanne)       Date:  2017-07-20       Impact factor: 5.555

3.  Hemoptysis as primary manifestation in three women with choriocarcinoma with pulmonary metastasis: a case series.

Authors:  Wenping Zhang; Bao Liu; Jizhen Wu; Beibei Sun
Journal:  J Med Case Rep       Date:  2017-04-16
  3 in total

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