Literature DB >> 26721636

Receiver Operating Characteristic Curve Analysis of Screening Tools for Bipolar Disorder Comorbid With ADHD in Schoolchildren.

Mara L Cordeiro1,2,3, Antonio C Farias2,4, Peter C Whybrow1, Erico P G Felden5, Alexandre Cunha2, Vilmar da Veiga2, Cássia R Benko2, James T McCracken1.   

Abstract

Objective: We compared Child Behavior Checklist (CBCL)-AAA (Attention Problems, Aggressive Behavior, and Anxious/Depressed) and Parent-Young Mania Rating Scale (P-YMRS) profiles in Brazilian children with ADHD, pediatric-onset bipolar disorder (PBD), and PBD + ADHD. Method: Following analyses of variance or Kruskal-Wallis tests with multiple-comparison Least Significant Difference (LSD) or Dunn's Tests, thresholds were determined by Mann-Whitney U Tests and receiver operating characteristic (ROC) plots.
Results: Relative to ADHD, PBD and PBD + ADHD groups scored higher on the Anxious/Depressed, Thought Problems, Rule-Breaking, and Aggressive Behavior subscales and Conduct/Delinquency Diagnostic Scale of the CBCL; all three had similar attention problems. The PBD and PBD + ADHD groups scored higher than the ADHD and healthy control (HC) groups on all CBCL problem scales. The AAA-profile ROC had good diagnostic prediction of PBD + ADHD. PBD and PBD-ADHD were associated with (similarly) elevated P-YMRS scores.
Conclusion: The CBCL-PBD and P-YMRS can be used to screen for manic behavior and assist in differential diagnosis.

Entities:  

Keywords:  ADHD; bipolar; diagnostic validity; receiver operating characteristic

Year:  2015        PMID: 26721636     DOI: 10.1177/1087054715620897

Source DB:  PubMed          Journal:  J Atten Disord        ISSN: 1087-0547            Impact factor:   3.256


  1 in total

1.  Further Evidence of the Diagnostic Utility of the Child Behavior Checklist for Identifying Pediatric Bipolar I Disorder.

Authors:  Amy Yule; Maura Fitzgerald; Timothy Wilens; Janet Wozniak; K Yvonne Woodworth; Alexa Pulli; Mai Uchida; Stephen V Faraone; Joseph Biederman
Journal:  Scand J Child Adolesc Psychiatr Psychol       Date:  2019-06-06
  1 in total

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