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Literature DB >> 26719436

Preclinical Assessment of a Fully Automated Multiplex PCR Panel for Detection of Central Nervous System Pathogens.

K E Hanson¹, E S Slechta², J A Killpack³, C Heyrend⁴, T Lunt², J A Daly⁵, A C Hemmert⁶, A J Blaschke⁷.

Abstract

We evaluated a multiplexed PCR panel for the detection of 16 bacterial, viral, and fungal pathogens in cerebrospinal fluid. Panel results were compared to routine testing, and discrepancies were resolved by additional nucleic acid amplification tests or sequencing. Overall, the positive and negative agreements across methods were 92.9% and 91.9%, respectively.

Mesh：

Substances：
Reagent Kits, Diagnostic

Year: 2015 PMID： 26719436 PMCID： PMC4767945 DOI： 10.1128/JCM.02850-15

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

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