Literature DB >> 26719267

Determination of Sequences Required for Human Endogenous Retrovirus K Transduction and Its Recognition by Foreign Retroviral Virions.

Otto Erlwein1, Nathan P Sweeney1, Raffaele de Leon1, Gillian Wills1, Mark J Robinson1, Myra O McClure2.   

Abstract

Sequences necessary for transduction of human endogenous retrovirus (HERV)-Kcon, a consensus of the HERV-K(HML-2) family, were analyzed and found to reside in the leader/gag region. They act in an orientation-dependent way and consist of at least two sites working together. Having defined these sequences, we exploited this information to produce a simple system to investigate to what extent virions of HERV-Kcon, murine leukemia virus, and HIV-1 have the ability to transduce each other's genomes, leading to potential contamination of gene therapy vectors.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26719267      PMCID： PMC4810645          DOI： 10.1128/JVI.02731-15

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  17 in total

1.  Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design.

Authors:  Giulietta Maruggi; Simona Porcellini; Giulia Facchini; Serena K Perna; Claudia Cattoglio; Daniela Sartori; Alessandro Ambrosi; Axel Schambach; Christopher Baum; Chiara Bonini; Chiara Bovolenta; Fulvio Mavilio; Alessandra Recchia
Journal:  Mol Ther       Date:  2009-03-17       Impact factor: 11.454

Review 2.  How retroviruses select their genomes.

Authors:  Victoria D'Souza; Michael F Summers
Journal:  Nat Rev Microbiol       Date:  2005-08       Impact factor: 60.633

3.  Characterization of human endogenous retroviral elements in the blood of HIV-1-infected individuals.

Authors:  Rafael Contreras-Galindo; Mark H Kaplan; Angie C Contreras-Galindo; Marta J Gonzalez-Hernandez; Ilaria Ferlenghi; Fabiola Giusti; Eric Lorenzo; Scott D Gitlin; Michael H Dosik; Yasuhiro Yamamura; David M Markovitz
Journal:  J Virol       Date:  2011-10-26       Impact factor: 5.103

4.  Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K-Related Sequences.

Authors:  Rafael Contreras-Galindo; Mark H Kaplan; Derek Dube; Marta J Gonzalez-Hernandez; Susana Chan; Fan Meng; Manhong Dai; Gilbert S Omenn; Scott D Gitlin; David M Markovitz
Journal:  J Virol       Date:  2015-04-29       Impact factor: 5.103

5.  High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells.

Authors:  Yves Durocher; Sylvie Perret; Amine Kamen
Journal:  Nucleic Acids Res       Date:  2002-01-15       Impact factor: 16.971

6.  Improved foamy virus vectors with minimal viral sequences.

Authors:  Grant Trobridge; Neil Josephson; George Vassilopoulos; Jaclynn Mac; David W Russell
Journal:  Mol Ther       Date:  2002-09       Impact factor: 11.454

7.  Identification of a generalised packaging sequence for D-type retroviruses and generation of a D-type retroviral vector.

Authors:  R G Vile; M Ali; E Hunter; M O McClure
Journal:  Virology       Date:  1992-08       Impact factor: 3.616

8.  The bovine leukemia virus encapsidation signal is discontinuous and extends into the 5' end of the gag gene.

Authors:  L M Mansky; A E Krueger; H M Temin
Journal:  J Virol       Date:  1995-06       Impact factor: 5.103

Review 9.  Retroviral vectors: post entry events and genomic alterations.

Authors:  Ali Nowrouzi; Hanno Glimm; Christof von Kalle; Manfred Schmidt
Journal:  Viruses       Date:  2011-04-29       Impact factor: 5.048

Review 10.  HIV infection and HERV expression: a review.

Authors:  Antoinette C van der Kuyl
Journal:  Retrovirology       Date:  2012-01-16       Impact factor: 4.602
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