Literature DB >> 26719243

Analysis of Assembly and Budding of Lujo Virus.

Shuzo Urata1, Jacqueline Weyer2, Nadia Storm2, Yukiko Miyazaki3, Petrus Jansen van Vuren2, Janusz Tadeusz Paweska2, Jiro Yasuda4.   

Abstract

The recently identified arenavirus Lujo virus (LUJV) causes fatal hemorrhagic fever in humans. We analyzed its mechanism of viral release driven by matrix protein Z and the cell surface glycoprotein precursor GPC. The L domains in Z are required for efficient virus-like particle release, but Tsg101, ALIX/AIP1, and Vps4A/B are unnecessary for budding. LUJV GPC is cleaved by site 1 protease (S1P) at the RKLM motif, and treatment with the S1P inhibitor PF-429242 reduced LUJV production.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26719243      PMCID： PMC4810620          DOI： 10.1128/JVI.03198-15

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  37 in total

1.  NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs.

Authors:  K J Lee; I S Novella; M N Teng; M B Oldstone; J C de La Torre
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

2.  RING finger Z protein of lymphocytic choriomeningitis virus (LCMV) inhibits transcription and RNA replication of an LCMV S-segment minigenome.

Authors:  T I Cornu; J C de la Torre
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103

3.  Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding.

Authors:  J E Garrus; U K von Schwedler; O W Pornillos; S G Morham; K H Zavitz; H E Wang; D A Wettstein; K M Stray; M Côté; R L Rich; D G Myszka; W I Sundquist
Journal:  Cell       Date:  2001-10-05       Impact factor: 41.582

4.  The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

Authors:  O Lenz; J ter Meulen; H D Klenk; N G Seidah; W Garten
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-16       Impact factor: 11.205

5.  Endoproteolytic processing of the lymphocytic choriomeningitis virus glycoprotein by the subtilase SKI-1/S1P.

Authors:  Winfried R Beyer; Dennis Pöpplau; Wolfgang Garten; Dorothee von Laer; Oliver Lenz
Journal:  J Virol       Date:  2003-03       Impact factor: 5.103

6.  Characterization of the arenavirus RING finger Z protein regions required for Z-mediated inhibition of viral RNA synthesis.

Authors:  Tatjana I Cornu; Juan Carlos de la Torre
Journal:  J Virol       Date:  2002-07       Impact factor: 5.103

7.  AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.

Authors:  Bettina Strack; Arianna Calistri; Stewart Craig; Elena Popova; Heinrich G Göttlinger
Journal:  Cell       Date:  2003-09-19       Impact factor: 41.582

8.  Lassa virus Z protein is a matrix protein and sufficient for the release of virus-like particles [corrected].

Authors:  Thomas Strecker; Robert Eichler; Jan ter Meulen; Winfried Weissenhorn; Hans Dieter Klenk; Wolfgang Garten; Oliver Lenz
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

9.  Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding.

Authors:  Jiro Yasuda; Eric Hunter; Mitsuyoshi Nakao; Hisatoshi Shida
Journal:  EMBO Rep       Date:  2002-07       Impact factor: 8.807

10.  Nedd4 regulates egress of Ebola virus-like particles from host cells.

Authors:  Jiro Yasuda; Mitsuyoshi Nakao; Yoshihiro Kawaoka; Hisatoshi Shida
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103
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  3 in total

1.  A Proteomics Survey of Junín Virus Interactions with Human Proteins Reveals Host Factors Required for Arenavirus Replication.

Authors:  Christopher M Ziegler; Philip Eisenhauer; Jamie A Kelly; Loan N Dang; Vedran Beganovic; Emily A Bruce; Benjamin R King; David J Shirley; Marion E Weir; Bryan A Ballif; Jason Botten
Journal:  J Virol       Date:  2018-01-30       Impact factor: 5.103

2.  Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor.

Authors:  Pollyanna Stephanie Gomes; Monique Pacheco Duarte Carneiro; Patrícia de Almeida Machado; Valter Viana de Andrade-Neto; Alessandra Marcia da Fonseca-Martins; Amy Goundry; João Vitor Marques Pereira da Silva; Daniel Claudio Oliveira Gomes; Ana Paula Cabral de Araujo Lima; Vítor Ennes-Vidal; Ana Carolina Rennó Sodero; Salvatore Giovanni De-Simone; Herbert L de Matos Guedes
Journal:  Curr Issues Mol Biol       Date:  2022-05-09       Impact factor: 2.976

3.  Molecular Mechanisms Underlying the Cellular Entry and Host Range Restriction of Lujo Virus.

Authors:  Takeshi Saito; Takanari Hattori; Kosuke Okuya; Rashid Manzoor; Hiroko Miyamoto; Masahiro Kajihara; Ayato Takada
Journal:  mBio       Date:  2022-02-15       Impact factor: 7.867
  3 in total

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