Mehmet Tetikoglu1, Fatih Temizturk2, Haci Murat Sagdik1, Serdar Aktas1, Fatih Ozcura3, Yasemin Ozkan2, Sule Temizturk2. 1. a Assistant Professor, Department of Ophthalmology , Dumlupinar University School of Medicine , Kutahya , Turkey. 2. b Assistant Professor, Department of Physical Medicine and Rehabilitation , Dumlupinar University School of Medicine , Kutahya , Turkey. 3. c Associate Professor, Department of Ophthalmology , Dumlupinar University School of Medicine , Kutahya , Turkey.
Abstract
PURPOSE: To evaluate the effect of rheumatoid arthritis (RA) on choroid, retinal nerve fiber layer (RNFL), and foveal thickness using spectral domain optical coherence tomography (OCT). METHODS: Fifty patients with RA and forty-one healthy volunteers were enrolled in this study. The subfoveal, perifoveal choroidal, RNFL, and foveal thicknesses were measured by spectral domain OCT. RESULTS: The mean subfoveal, nasal, and temporal choroidal thicknesses in RA individuals were significantly higher than those in the control group (p ˂ 0.05). However, there was no significant difference between the RA and healthy group regarding RNFL and foveal thickness (p ˃ 0.05). A significant correlation was found between rheumatoid factor (RF) and the subfoveal temporal choroidal thickness. CONCLUSION: Choroidal thickness in RA patients was higher than that in healthy participants. Choroidal thickening showed a positive correlation with RF, which may be an indicator for systemic vasculitis.
PURPOSE: To evaluate the effect of rheumatoid arthritis (RA) on choroid, retinal nerve fiber layer (RNFL), and foveal thickness using spectral domain optical coherence tomography (OCT). METHODS: Fifty patients with RA and forty-one healthy volunteers were enrolled in this study. The subfoveal, perifoveal choroidal, RNFL, and foveal thicknesses were measured by spectral domain OCT. RESULTS: The mean subfoveal, nasal, and temporal choroidal thicknesses in RA individuals were significantly higher than those in the control group (p ˂ 0.05). However, there was no significant difference between the RA and healthy group regarding RNFL and foveal thickness (p ˃ 0.05). A significant correlation was found between rheumatoid factor (RF) and the subfoveal temporal choroidal thickness. CONCLUSION: Choroidal thickness in RApatients was higher than that in healthy participants. Choroidal thickening showed a positive correlation with RF, which may be an indicator for systemic vasculitis.
Authors: Arnaldo Dias-Santos; Joana Tavares Ferreira; Sofia Pinheiro; João Paulo Cunha; Marta Alves; Ana L Papoila; Maria Francisca Moraes-Fontes; Rui Proença Journal: Int J Retina Vitreous Date: 2020-04-21