| Literature DB >> 26716762 |
Eric T Newcomb1, Phil C Knutson1, Blaine A Pedersen1, Eric M Ferreira1.
Abstract
The first total synthesis of (±)-gelsenicine is reported. The synthetic route is highly efficient (13 steps), featuring (1) a pivotal metal-catalyzed isomerization/rearrangement process that forges the central core of the molecule and (2) two facile C-N bond-forming steps that establish the flanking heterocycles.Entities:
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Year: 2015 PMID： 26716762 PMCID： PMC4732274 DOI： 10.1021/jacs.5b12263
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419