Literature DB >> 2671610

Protective role of human antibody to the fusion protein of measles virus.

T A Sato1, T Kohama, A Sugiura.   

Abstract

Absorption of a pooled human gamma globulin preparation with acetone-treated measles virus-infected cells removed all antibodies to measles virus antigens except a portion of the antibody to the fusion (F) protein. The residual anti-F antibody had hemolysis-inhibiting and virus-neutralizing activities, inhibited spread of infection through cell fusion, and was effective in protection of passively immunized mice from fatal measles encephalitis, providing evidence for the protective role of human antibody to the F protein of measles virus.

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Year:  1989        PMID： 2671610     DOI： 10.1111/j.1348-0421.1989.tb02010.x

Source DB:  PubMed          Journal:  Microbiol Immunol        ISSN： 0385-5600            Impact factor:   1.955


  2 in total

1.  Characterization of a natural mutation in an antigenic site on the fusion protein of measles virus that is involved in neutralization.

Authors:  J Fayolle; B Verrier; R Buckland; T F Wild
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

2.  Human HLA class I- and HLA class II-restricted cloned cytotoxic T lymphocytes identify a cluster of epitopes on the measles virus fusion protein.

Authors:  R S van Binnendijk; J P Versteeg-van Oosten; M C Poelen; H F Brugghe; P Hoogerhout; A D Osterhaus; F G Uytdehaag
Journal:  J Virol       Date:  1993-04       Impact factor: 5.103
  2 in total

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